Nerolidol: a sesquiterpene alcohol with multi-faceted pharmacological and biological activities

WK Chan, LTH Tan, KG Chan, LH Lee, BH Goh - Molecules, 2016 - mdpi.com
Nerolidol (3, 7, 11-trimethyl-1, 6, 10-dodecatrien-3-ol) is a naturally occurring sesquiterpene
alcohol that is present in various plants with a floral odor. It is synthesized as an intermediate …

Impact of human schistosomiasis in sub-Saharan Africa

AF Adenowo, BE Oyinloye, BI Ogunyinka… - Brazilian Journal of …, 2015 - SciELO Brasil
abstract Schistosomiasis, a neglected tropical disease of poverty ranks second among the
most widespread parasitic disease in various nations in sub-Saharan Africa. Neglected …

Schistosoma “eggs-iting” the host: granuloma formation and egg excretion

C Schwartz, PG Fallon - Frontiers in immunology, 2018 - frontiersin.org
Schistosomiasis is a major cause of morbidity in humans invoked by chronic infection with
parasitic trematodes of the genus Schistosoma. Schistosomes have a complex life-cycle …

Revisiting the mechanisms of immune evasion employed by human parasites

M Chulanetra, W Chaicumpa - Frontiers in cellular and infection …, 2021 - frontiersin.org
For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

[HTML][HTML] Serological approaches for the diagnosis of schistosomiasis–A review

R Hinz, NG Schwarz, A Hahn, H Frickmann - Molecular and Cellular …, 2017 - Elsevier
Schistosomiasis is a common disease in endemic areas of Sub-Saharan Africa, South
America and Asia. It is rare in Europe, mainly imported from endemic countries due to …

Schistosome-induced fibrotic disease: the role of hepatic stellate cells

JP Carson, GA Ramm, MW Robinson, DP McManus… - Trends in …, 2018 - cell.com
Hepatic fibrosis is a common pathology in various liver diseases. Hepatic stellate cells
(HSCs) are the main cell type responsible for collagen deposition and fibrosis formation in …

Metabolic programming of macrophages: implications in the pathogenesis of granulomatous disease

JL Wilson, HK Mayr, T Weichhart - Frontiers in immunology, 2019 - frontiersin.org
Metabolic reprogramming is rapidly gaining appreciation in the etiology of immune cell
dysfunction in a variety of diseases. Tuberculosis, schistosomiasis, and sarcoidosis …

Chronic intestinal schistosomiasis caused by co-infection with Schistosoma intercalatum and Schistosoma mansoni

P Kołodziej, B Szostakowska, A Lass… - The Lancet Infectious …, 2024 - thelancet.com
Summary The Grand Round concerns a 24-year-old man from Zimbabwe who was studying
and living in Poland. The patient had been complaining of abdominal pain, fatigue …

[HTML][HTML] The chronic enteropathogenic disease schistosomiasis

DU Olveda, RM Olveda, DP McManus, P Cai… - International Journal of …, 2014 - Elsevier
Schistosomiasis is a chronic enteropathogenic disease caused by blood flukes of the genus
Schistosoma. The disease afflicts approximately 240 million individuals globally, causing …

The idiosyncratic efficacy of spironolactone-loaded PLGA nanoparticles against murine intestinal schistosomiasis

WE Abd El Hady, GA El-Emam, NE Saleh… - International Journal …, 2023 - Taylor & Francis
Background Schistosomiasis is a chronic debilitating parasitic disease accompanied with
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …