Vitiligo is an acquired chronic depigmenting disorder of the skin, with an estimated
prevalence of 0.5% of the general population, characterized by the development of white …

The disorder now known as vitiligo was first described by Claude Nicolas Le Cat in 1765. 1
However, the first specific consideration of a genetic component in vitiligo did not come until …

We performed a meta-analysis of 2 genome-wide association studies of coronary artery
disease comprising 1,515 cases and 5,019 controls followed by replication studies in 15,460 …

Vitiligo is the most common depigmenting disorder resulting from the loss of melanocytes
from the basal epidermal layer. The pathogenesis of the disease is likely multifactorial and …

IL-17 is involved in the pathogenesis of several autoimmune diseases; however its role in
vitiligo has not been well defined. Emerging human and mouse studies have demonstrated …

Vitiligo is a complex disease in which autoimmune destruction of epidermal melanocytes
results in patches of depigmented white skin. Vitiligo has an estimated prevalence of about …

Generalized vitiligo (GV) is a complex disease in which patchy depigmentation results from
autoimmune loss of melanocytes from affected regions. Genetic analyses of GV span six …

Immune‐mediated responses are consistently observed in progressing vitiligo at the edge of
depigmenting patches. Besides the role of the adaptive immune system, the profile of the …

Vitiligo is an autoimmune disease with a strong genetic component, characterized by areas
of depigmented skin resulting from loss of epidermal melanocytes. Genetic factors are …

Vitiligo is an asymptomatic but cosmetically disfiguring disorder that results in the formation
of depigmented patches on skin and/or mucosae. Vitiligo can be segmental or non …