Comparative protein structure modeling of genes and genomes
MA Martí-Renom, AC Stuart, A Fiser… - Annual review of …, 2000 - annualreviews.org
▪ Abstract Comparative modeling predicts the three-dimensional structure of a given protein
sequence (target) based primarily on its alignment to one or more proteins of known …
sequence (target) based primarily on its alignment to one or more proteins of known …
From genes to protein structure and function: novel applications of computational approaches in the genomic era
J Skolnick, JS Fetrow - Trends in biotechnology, 2000 - cell.com
The genome-sequencing projects are providing a detailed 'parts list'of life. A key to
comprehending this list is understanding the function of each gene and each protein at …
comprehending this list is understanding the function of each gene and each protein at …
Using evolutionary data to make sense of macromolecules with a “face‐lifted” ConSurf
B Yariv, E Yariv, A Kessel, G Masrati, AB Chorin… - Protein …, 2023 - Wiley Online Library
The ConSurf web‐sever for the analysis of proteins, RNA, and DNA provides a quick and
accurate estimate of the per‐site evolutionary rate among homologues. The analysis reveals …
accurate estimate of the per‐site evolutionary rate among homologues. The analysis reveals …
Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase
G Petzold, ES Fischer, NH Thomä - Nature, 2016 - nature.com
Thalidomide and its derivatives, lenalidomide and pomalidomide, are immune modulatory
drugs (IMiDs) used in the treatment of haematologic malignancies,. IMiDs bind CRBN, the …
drugs (IMiDs) used in the treatment of haematologic malignancies,. IMiDs bind CRBN, the …
Low ABA concentration promotes root growth and hydrotropism through relief of ABA INSENSITIVE 1-mediated inhibition of plasma membrane H+-ATPase 2
R Miao, W Yuan, Y Wang, I Garcia-Maquilon… - Science …, 2021 - science.org
The hab1-1abi1-2abi2-2pp2ca-1 quadruple mutant (Qabi2-2) seedlings lacking key
negative regulators of ABA signaling, namely, clade A protein phosphatases type 2C …
negative regulators of ABA signaling, namely, clade A protein phosphatases type 2C …
A prevalent peptide-binding domain guides ribosomal natural product biosynthesis
BJ Burkhart, GA Hudson, KL Dunbar… - Nature chemical …, 2015 - nature.com
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a rapidly
growing class of natural products. RiPP precursor peptides can undergo extensive …
growing class of natural products. RiPP precursor peptides can undergo extensive …
Comparative protein modelling by satisfaction of spatial restraints
A Šali, TL Blundell - Journal of molecular biology, 1993 - Elsevier
We describe a comparative protein modelling method designed to find the most probable
structure for a sequence given its alignment with related structures. The three dimensional …
structure for a sequence given its alignment with related structures. The three dimensional …
Structural insights into tetraspanin CD9 function
R Umeda, Y Satouh, M Takemoto… - Nature …, 2020 - nature.com
Tetraspanins play critical roles in various physiological processes, ranging from cell
adhesion to virus infection. The members of the tetraspanin family have four membrane …
adhesion to virus infection. The members of the tetraspanin family have four membrane …
Modeller: generation and refinement of homology-based protein structure models
Publisher Summary Functional characterization of a protein sequence is one of the most
frequent problems in biology. This task is usually facilitated by accurate three-dimensional …
frequent problems in biology. This task is usually facilitated by accurate three-dimensional …
The Arabidopsis CORONATINE INSENSITIVE1 Protein Is a Jasmonate Receptor
Jasmonates play a number of diverse roles in plant defense and development.
CORONATINE INSENSITIVE1 (COI1), an F-box protein essential for all the jasmonate …
CORONATINE INSENSITIVE1 (COI1), an F-box protein essential for all the jasmonate …