Narcolepsy: Comorbidities, complexities and future directions

S Gudka, E Haynes, J Scotney, S Mukherjee… - Sleep Medicine …, 2022 - Elsevier
Patients with narcolepsy live with a lifelong sleep-wake disorder, impairing their quality of
life, productivity, educational and employment outcomes. Clinicians are becoming aware …

How hypocretin agonists may improve the quality of wake in narcolepsy

JL Justinussen, C Egebjerg, BR Kornum - Trends in Molecular Medicine, 2023 - cell.com
Excessive daytime sleepiness (EDS) is a complex symptom characterized by a strong urge
to sleep during daytime accompanied by problems such as attention deficits, anxiety, and …

Narcolepsy and psychiatric disorders: A bidirectional Mendelian randomization study

B Li, Z Gao, Y He, Y Tian, Y Shen, G Yu, X Geng… - Journal of Psychiatric …, 2024 - Elsevier
Since the introduction of the concept of narcolepsy, there has been a proliferation of
discussions about its association with psychiatry. To elucidate the causal role of narcolepsy …

[HTML][HTML] Associations between psychiatric comorbid disorders and executive dysfunctions in hypocretin-1 deficient pediatric narcolepsy type1

BH Hansen, HN Andresen, J Gjesvik, PM Thorsby… - Sleep Medicine, 2023 - Elsevier
Abstract Objective/Background Psychiatric symptoms and cognitive deficits add significantly
to impairment in academic achievement and quality of life in patients with narcolepsy. The …

Sex and age differences in the association between anxiety disorders and narcolepsy: a nationwide population-based case control study

TY Chen, CH Huang, CH Chung, WC Mao… - Journal of Affective …, 2020 - Elsevier
Background To examine the association between narcolepsy and anxiety disorders.
Methods This population-based, retrospective case-control study analyzed Taiwan's …

Neuropsychiatric correlates of narcolepsy

AS BaHammam, K Alnakshabandi… - Current Psychiatry …, 2020 - Springer
Abstract Purpose of Review The complex nature of narcolepsy symptoms, along with the use
of stimulants and anticataplectic medications, poses diagnostic difficulties in terms of …

[HTML][HTML] Alexithymia, impulsiveness, emotion, and eating dyscontrol: similarities and differences between narcolepsy type 1 and type 2

C Del Bianco, M Ulivi, C Liguori, A Pisani… - Sleep and Biological …, 2023 - Springer
Non-sleep symptoms, as depression, anxiety and overweight, are often encountered in
narcoleptic patients. The purposes of this study are to evaluate mood, impulsiveness …

Anxiety and depression in patients with narcolepsy

MJ Abenza‐Abildua, E Suárez‐Gisbert… - Journal of Sleep …, 2023 - Wiley Online Library
We analysed the co‐existence of psychopathology in patients with narcolepsy at our centre.
We performed an observational retrospective descriptive analysis of patients with a …

Recognizing the symptom spectrum of narcolepsy to improve timely diagnosis: a narrative review

L Quaedackers, S Pillen, S Overeem - Nature and Science of …, 2021 - Taylor & Francis
Narcolepsy is a chronic sleep disorder with a strong negative impact on quality of life,
especially when untreated. Diagnostic delay is a persistent problem, with obvious …

Cardiovascular Risks in People With Narcolepsy: Expert Panel Consensus Recommendations

Y Kwon, AS Gami, S Javaheri… - Journal of the …, 2024 - ahajournals.org
Background Observational and retrospective studies suggest that people with narcolepsy
may have an increased prevalence of cardiovascular and cardiometabolic comorbidities …