Background Haemoglobinopathies constitute the commonest recessive monogenic
disorders worldwide, and the treatment of affected individuals presents a substantial global …

This article reviews key data and debates focused on relative sea-level changes since the
Last Interglacial (approximately the last 132,000 years) in the Mediterranean Basin, and …

Proponents of the model known as the “human revolution” claim that modern human
behaviors arose suddenly, and nearly simultaneously, throughout the Old World ca. 40 …

The timing of the dispersal of anatomically modern humans (AMH) out of Africa is a
fundamental question in human evolutionary studies. Existing data suggest a rapid coastal …

Equilibrium models of isolation by distance predict an increase in genetic differentiation with
geographic distance. Here we find a linear relationship between genetic and geographic …

Although aquatic resources are often seen as central to the development of post-Pleistocene
cultural complexity, most models of human evolution have all but ignored the role of aquatic …

It has been argued recently that the initial dispersal of anatomically modern humans from
Africa to southern Asia occurred before the volcanic “supereruption” of the Mount Toba …

Consideration of a range of evidence from geomorphology, palynology, biogeography and
vegetation/climate modelling suggests that a north-south 'savanna corridor'did exist through …

Recent research has provided increasing support for the origins of anatomically and
genetically “modern” human populations in Africa between 150,000 and 200,000 years ago …

Cutaneous synthesis of vitamin D by exposure to UVB is the principal source of vitamin D in
the human body. Our current clothing habits and reduced time spent outdoors put us at risk …