Giardia duodenalis: biology and pathogenesis

RD Adam - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Giardia duodenalis captured the attention of Leeuwenhoek in 1681 while he was examining
his own diarrheal stool, but, ironically, it did not really gain attention as a human pathogen …

Unique endomembrane systems and virulence in pathogenic protozoa

MF Wiser - Life, 2021 - mdpi.com
Virulence in pathogenic protozoa is often tied to secretory processes such as the expression
of adhesins on parasite surfaces or the secretion of proteases to assisted in tissue invasion …

Mlf mediates proteotoxic response via formation of cellular foci for protein folding and degradation in Giardia

M Vinopalová, L Arbonová, Z Füssy, V Dohnálek… - PLoS …, 2024 - journals.plos.org
Myeloid leukemia factor 1 (Mlf1) was identified as a proto-oncoprotein that affects
hematopoietic differentiation in humans. However, its cellular function remains elusive …

Giardia lamblia: identification of peroxisomal-like proteins

K Acosta-Virgen, B Chávez-Munguía… - Experimental …, 2018 - Elsevier
The protozoan parasite Giardia lamblia has traditionally been reported as lacking
peroxisomes, organelles involved in fatty acid metabolism and detoxification of reactive …

Staging Encystation Progression in Giardia lamblia Using Encystation-Specific Vesicle Morphology and Associating Molecular Markers

EB Thomas, R Sutanto, RS Johnson… - Frontiers in cell and …, 2021 - frontiersin.org
Differentiation into environmentally resistant cysts is required for transmission of the
ubiquitous intestinal parasite Giardia lamblia. Encystation in Giardia requires the production …

Membrane-Associated Proteins in Giardia lamblia

MC Touz, C Feliziani, AS Rópolo - Genes, 2018 - mdpi.com
The manner in which membrane-associated proteins interact with the membrane defines
their subcellular fate and function. This interaction relies on the characteristics of the …

Symbiotic origin of eukaryotic nucleus: from cell body to neo-energide

F Baluška, S Lyons - Concepts in Cell Biology-History and Evolution, 2018 - Springer
Several aspects of the eukaryotic cell suggest that the nucleus is of symbiotic origin. The
nucleus forms, via its perinuclear structures, the primary eukaryotic agent known also as the …

A cytonaut's guide to protein trafficking in Giardia lamblia

C Faso, AB Hehl - Advances in parasitology, 2019 - Elsevier
Over the past years, the subcellular organization of the Excavata member Giardia lamblia
(syn. duodenalis, intestinalis) has been investigated in considerable detail. There are …

Giardia intestinalis coiled-coil cytolinker protein 259 interacts with actin and tubulin

O Rojas-Gutiérrez, A Pérez-Rangel… - Parasitology …, 2021 - Springer
Giardia intestinalis is a human parasite that causes a diarrheal disease in developing
countries. G. intestinalis has a cytoskeleton (CSK) composed of microtubules and …

The protein 14-3-3: A functionally versatile molecule in Giardia duodenalis

M Lalle, A Fiorillo - Advances in Parasitology, 2019 - Elsevier
Giardia duodenalis is a cosmopolitan zoonotic protozoan parasite causing giardiasis, one of
the most common diarrhoeal diseases in human and animals. Beyond its public health …