Aminothiophenes are important five-membered heterocyclic building blocks in organic
synthesis, and the chemistry of these small molecules is still developing based on the …

Bacterial persisters are a subpopulation of cells that exhibit phenotypic resistance during
exposure to a lethal dose of antibiotics. They are difficult to target and thought to contribute …

Some new pyridinethione and thienopyridine derivatives have been synthesized and
evaluated for their antiproliferative activity using the MTT assay. Nicotinamide derivatives 3 …

In the present study, we have designed imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-
b] thiazole derivatives from earlier reported imidazo [1, 2-a] pyridine based Mycobacterium …

Despite decades of dedicated research, there remains a dire need for new drugs against
tuberculosis (TB). Current therapies are generations old and problematic. Resistance to …

Tuberculosis (TB), one of the most prevalent infections, is on the rise today. Although there
are drugs available in the market to combat this lethal disorder, there are several …

This review presents the most elegant and promising set of synthetic routes for the synthesis
of 2‐aminothiophenes by the Gewald reaction. This reaction has applications in several …

Abstract New N‐substituted‐2‐amino‐4, 5, 6, 7‐tetrahydrothieno [2, 3‐c] pyridine derivatives
were synthesized employing a convenient one‐pot three‐component method and their …

Abstract A palladium catalyzed decarboxylative [4+ 2] cycloaddition of vinyl
benzoxazinanones with 2‐arylidene indan‐1, 3‐dione has been established, which afford a …

Highlights•The most recently studied drug targets are reviewed.•The protein–protein
interaction network was generated using STRING database.•Hits and leads were discovered …