An update on autophagy disorders
HS Dafsari, D Martinelli, A Saffari… - Journal of Inherited …, 2025 - Wiley Online Library
Macroautophagy is a highly conserved cellular pathway for the degradation and recycling of
defective cargo including proteins, organelles, and macromolecular complexes. As …
defective cargo including proteins, organelles, and macromolecular complexes. As …
TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression
D Remy, S Antoine-Bally, S de Toqueville, C Jolly… - Developmental Cell, 2024 - cell.com
Summary The phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin
(mTOR) pathway is frequently hyperactivated in triple-negative breast cancers (TNBCs) …
(mTOR) pathway is frequently hyperactivated in triple-negative breast cancers (TNBCs) …
[HTML][HTML] Autophagosome turnover requires Arp2/3 complex-mediated maintenance of lysosomal integrity
CJ Theodore, LH Wagner, KG Campellone - bioRxiv, 2024 - ncbi.nlm.nih.gov
Autophagy is an intracellular degradation process that maintains homeostasis, responds to
stress, and plays key roles in the prevention of aging and disease. Autophagosome …
stress, and plays key roles in the prevention of aging and disease. Autophagosome …