Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Red blood cells (RBCs) have historically been considered passive bystanders in
thrombosis. However, clinical and epidemiological studies have associated quantitative and …

Importance Red blood cell transfusion is a common medical intervention with benefits and
harms. Objective To provide recommendations for use of red blood cell transfusion in adults …

Red blood cell (RBC) storage in the blood bank promotes the progressive accumulation of
metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant …

Background It is uncertain whether the duration of red-cell storage affects mortality after
transfusion among critically ill adults. Methods In an international, multicenter, randomized …

Cell-based medicine has made great advances in clinical diagnosis and therapy for various
refractory diseases, inducing a growing demand for cell preservation as support technology …

Significant research has focused individually on blood donors, product preparation and
storage, and optimal transfusion practice. To better understand the interplay between these …

Permanent availability of red blood cells (RBCs) for transfusion depends on refrigerated
storage, during which morphologically altered RBCs accumulate. Among these, a …

Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …

BACKGROUND RBC transfusion effectiveness varies due to donor, component, and
recipient factors. Prior studies identified characteristics associated with variation in …