Nanozymes With Osteochondral Regenerative Effects: An Overview of Mechanisms and Recent Applications

X Sun, X Xu, X Yue, T Wang, Z Wang… - Advanced …, 2024 - Wiley Online Library
With the discovery of the intrinsic enzyme‐like activity of metal oxides, nanozymes garner
significant attention due to their superior characteristics, such as low cost, high stability, multi …

Development of nanozymes for promising alleviation of COVID-19-associated arthritis

D Li, B Zhao, P Zhuang, X Mei - Biomaterials Science, 2023 - pubs.rsc.org
The COVID-19 pandemic caused by SARS-CoV-2 has been identified as a culprit in the
development of a variety of disorders, including arthritis. Although the emergence of arthritis …

NIR triggered photocatalytic and photothermal bifunctional MOF nanozyme using for improving osteoarthritis microenvironment by repairing injured chondrocytes of …

S Xu, Y Lin, X Zhao, Z Liang, Y Hu, Z Chen… - Chemical Engineering …, 2023 - Elsevier
Osteoarthritis (OA) is one of the leading causes of chronic disability in the elderly. Effective
clinical interventions for OA are still lacking, and new therapeutic measures are urgently …

Biomimetic Prussian blue nanozymes with enhanced bone marrow-targeting for treatment of radiation-induced hematopoietic injury

B Zhang, G Chen, X Wu, Y Li, Y Xiao, J Li, L He, Y Li… - Biomaterials, 2023 - Elsevier
There is an urgent medical need to develop effective therapies that can ameliorate damage
to the radiation-exposed hematopoietic system. Nanozymes with robust antioxidant …

[HTML][HTML] Novel molecule BBC0901 inhibits BRD4 and acts as a catabolic regulator in the pathogenesis of osteoarthritis

H Lee, J Nam, H Jang, YS Park, MH Son, IH Lee… - Biomedicine & …, 2023 - Elsevier
Osteoarthritis (OA) is induced by matrix degradation and inflammation mediated by bromo-
domain-containing protein 4 (BRD4)-dependent catabolic factors. BRD4 acts as both a …

Alloy nanozyme-reinforced hyaluronic acid-based hydrogel with wound environment-responsive properties for synergistically accelerating infectious wound healing

Y Yuan, H Zhao, X Yin, D Wang, X Mei… - International Journal of …, 2024 - Elsevier
The recovery of infectious wound tissues presents a significant global health challenge due
to the impediments posed by the harsh healing microenvironment, which includes ongoing …

Insights into the mechanism of a substituted metal center regulating the enzymatic activity of Prussian blue analogues for catalytic antioxidation

G Zhou, Q Dong, Z Li, F Yang, X Shen, Q Liu, G Fang… - Nanoscale, 2024 - pubs.rsc.org
Atom engineering has been demonstrated to be an efficient strategy for optimizing the
activities of Prussian blue analogue (PBA)-based nanozymes. Herein, using a series of …

[HTML][HTML] Recent Advances in ROS-Scavenging Metallic Nanozymes for Anti-Inflammatory Diseases: A Review

A Mohapatra, IK Park - Chonnam Medical Journal, 2023 - ncbi.nlm.nih.gov
Oxidative stress and dysregulated inflammatory responses are the hallmarks of inflammatory
disorders, which are key contributors to high mortality rates and impose a substantial …

A Reactive Oxygen Species “Sweeper” Based on Hollow Mesopore Cerium Oxide Nanospheres for Targeted and Anti-Inflammatory Management of Osteoarthritis

G Chen, L Cui, P Luo, J Fang, X Xie… - ACS Applied Materials & …, 2024 - ACS Publications
Osteoarthritis (OA) is a progressive joint disorder characterized by sustained oxidative
stress, chronic inflammation, and the degradation of cartilage. Despite extensive research …