In a state of balance between oxidants and antioxidants, free radicals play an advantageous
role of “redox messengers”. In a state of oxidative stress, they trigger a cascade of events …

Proper brain development essentially depends on the timed availability of sufficient amounts
of thyroid hormone (TH). This, in turn, necessitates a tightly regulated expression of TH …

Background Quercetin is a major flavonoid in various plants. It possesses the multiple
pharmacological actions like vascular integrity and regulatory action of the blood-brain …

Ever since the discovery of thyroid hormone deficiency as the primary cause of cretinism in
the second half of the 19th century, the crucial role of thyroid hormone (TH) signaling in …

Thyroid hormones (THs) play an important role in the regulation of energy metabolism. They
also take part in processes associated with the central nervous system (CNS), including …

Endocrine disruptors (EDs), chemical substances widely used in industry and ubiquitously
distributed in the environment, are able to interfere with the synthesis, release, transport …

This study detected the impact of maternal carbamazepine (CBZ) on the fetal
neuroendocrine-cytokines axis. 25 or 50 mg/kg of CBZ was intraperitoneally administrated to …

Mutations in serotonin pathway genes, especially the serotonergic receptor subunit gene
HTR3A, are associated with autism. However, the association of HTR3A deficiency with …

Objective The drug‐refractory epilepsy (DRE) in children is commonly observed but the
underlying mechanisms remain elusive. We examined whether fatty acids (FAs) and lipids …

Melanin, a ubiquitous dark pigment, plays important roles in the immune system, including
scavenging reactive oxygen species formed in response to ultraviolet radiation absorption …