Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are
characterized by uncontrolled activation of intestinal immune cells in a genetically …

Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …

11.1. General The treatment strategy for ulcerative colitis [UC] is mainly based on the
severity, distribution [proctitis, left-sided, extensive] 1 and pattern of disease. The latter …

Abstract IL-12 and IL-23 are closely related cytokines with important roles in the regulation of
tissue inflammation. Converging evidence from studies in mice, human observational …

Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

Objective Patients with IBD display substantial heterogeneity in clinical characteristics. We
hypothesise that individual differences in the complex interaction of the host genome and …

Crohn disease is a chronic idiopathic inflammatory bowel disease condition characterized
by skip lesions and transmural inflammation that can affect the entire gastrointestinal tract …

Background Stricturing and penetrating complications account for substantial morbidity and
health-care costs in paediatric and adult onset Crohn's disease. Validated models to predict …

Crohn's disease (CD), a form of inflammatory bowel disease, has a higher prevalence in
Ashkenazi Jewish than in non-Jewish European populations. To define the role of …