Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

[PDF][PDF] Noninvasive, quantitative assessment of liver fat by MRI‐PDFF as an endpoint in NASH trials

C Caussy, SB Reeder, CB Sirlin, R Loomba - Hepatology, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver
disease worldwide, and the progressive form of this condition, nonalcoholic steatohepatitis …

Magnetic resonance elastography vs transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsy-proven …

CC Park, P Nguyen, C Hernandez, R Bettencourt… - Gastroenterology, 2017 - Elsevier
Background & Aims Magnetic resonance imaging (MRI) techniques and ultrasound-based
transient elastography (TE) can be used in noninvasive diagnosis of fibrosis and steatosis in …

[HTML][HTML] Noninvasive Diagnosis of NAFLD and NASH

VA Piazzolla, A Mangia - Cells, 2020 - mdpi.com
The aim of this review is to outline emerging biomarkers that can serve as early diagnostic
tools to identify patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic …

Nonalcoholic fatty liver disease

EM Brunt, VWS Wong, V Nobili, CP Day… - Nature reviews Disease …, 2015 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by excess accumulation
of fat in hepatocytes (nonalcoholic fatty liver (NAFL)); in up to 40% of individuals, there are …

[HTML][HTML] Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice

JH Zhou, JJ Cai, ZG She, HL Li - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

[PDF][PDF] Optimal threshold of controlled attenuation parameter with MRI‐PDFF as the gold standard for the detection of hepatic steatosis

C Caussy, MH Alquiraish, P Nguyen… - …, 2018 - Wiley Online Library
The optimal threshold of controlled attenuation parameter (CAP) for the detection of hepatic
steatosis using both M and XL probe is unknown in nonalcoholic fatty liver disease (NAFLD) …

[HTML][HTML] Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease

N Tamaki, N Ahlholm, PK Luukkonen… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND A pilot, single-center study showed that first-degree relatives of probands
with nonalcoholic fatty liver disease (NAFLD) cirrhosis have a high risk of advanced fibrosis …

Diagnostic value of MRI-PDFF for hepatic steatosis in patients with non-alcoholic fatty liver disease: a meta-analysis

J Gu, S Liu, S Du, Q Zhang, J Xiao, Q Dong, Y Xin - European radiology, 2019 - Springer
Objective To systematically review studies about the diagnostic accuracy of magnetic
resonance imaging proton density fat fraction (MRI-PDFF) in the classification of hepatic …

MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: clinical trials to clinical practice

PS Dulai, CB Sirlin, R Loomba - Journal of hepatology, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents one of the most common causes of
chronic liver disease, and its prevalence is rising worldwide. The occurrence of non …