A Fiordelisi, G Iaccarino, C Morisco, E Coscioni… - International journal of …, 2019 - mdpi.com
Inflammation is a key mechanism of cardiovascular diseases. It is an essential component of atherosclerosis and a significant risk factor for the development of cardiovascular events. In …
G protein-coupled receptor (GPCR) kinases (GRKs) are best known for their role in homologous desensitization of GPCRs. GRKs phosphorylate activated receptors and …
G protein-coupled receptors (GPCRs) are critical cellular sensors that mediate numerous physiological processes. In the heart, multiple GPCRs are expressed on various cell types …
PY Sato, JK Chuprun, M Schwartz… - Physiological …, 2015 - journals.physiology.org
G protein-coupled receptors (GPCRs) are important regulators of various cellular functions via activation of intracellular signaling events. Active GPCR signaling is shut down by GPCR …
G Santulli, A Wronska, K Uryu… - The Journal of …, 2014 - Am Soc Clin Investig
Drugs currently approved to coat stents used in percutaneous coronary interventions do not discriminate between proliferating vascular smooth muscle cells (VSMCs) and endothelial …
A Wronska, I Kurkowska‐Jastrzebska… - Acta …, 2015 - Wiley Online Library
Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. Innovative, more stringent diagnostic and prognostic biomarkers and effective treatment …
A Majdalawieh, HS Ro - Mediators of inflammation, 2010 - Wiley Online Library
NF‐κB comprises a family of transcription factors that are critically involved in various inflammatory processes. In this paper, the role of NF‐κB in inflammation and atherosclerosis …
G Santulli - microRNA: Basic Science: From Molecular Biology to …, 2015 - Springer
Endothelial cells (EC) and vascular smooth muscle cells (VSMC) are the main cell types within the vasculature. We describe here how microRNAs (miRs)—noncoding RNAs that …
Recently it has been demonstrated that catecholamines are produced and used by macrophages and mediate immune response. The aim of this study is to verify whether …