Strategies for developing sensitive and specific nanoparticle-based lateral flow assays as point-of-care diagnostic device

JH Soh, HM Chan, JY Ying - Nano Today, 2020 - Elsevier
From a home-based pregnancy self-testing kit, lateral flow assays (LFAs) have proliferated
and gained widespread utilization as point-of-care (POC) test kits. Their prevalence is due to …

Site-specific immobilization of recombinant antibody fragments through material-binding peptides for the sensitive detection of antigens in enzyme immunoassays

Y Kumada - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2014 - Elsevier
The immobilization of an antibody is one of the key technologies that are used to enhance
the sensitivity and efficiency of the detection of target molecules in immunodiagnosis and …

The Trypanosoma cruzi Antigen and Epitope Atlas: antibody specificities in Chagas disease patients across the Americas

AD Ricci, L Bracco, E Salas-Sarduy… - Nature …, 2023 - nature.com
During an infection the immune system produces pathogen-specific antibodies. These
antibody repertoires become specific to the history of infections and represent a rich source …

Sensitive and specific capture of polystyrene and polypropylene microplastics using engineered peptide biosensors

H Woo, SH Kang, Y Kwon, Y Choi, J Kim, DH Ha… - RSC …, 2022 - pubs.rsc.org
Owing to increased environmental pollution, active research regarding microplastics
circulating in the ocean has attracted significant interest in recent times. Microplastics …

Discovery of a polystyrene binding peptide isolated from phage display library and its application in peptide immobilization

X Qiang, K Sun, L Xing, Y Xu, H Wang, Z Zhou… - Scientific reports, 2017 - nature.com
Phage peptide display is a powerful technique for discovery of various target-specific
ligands. However, target-unrelated peptides can often be obtained and cause ambiguous …

Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation

A Katebi, R Varshochian, F Riazi-Rad… - Biomedicine & …, 2021 - Elsevier
Appropriate activation of macrophages is critical for the elimination of Leishmania parasites,
which resides in this cell. Some species of Leishmania (L.) fails to stimulate macrophages …

Development and Validation of an LC-MS/MS Method for Simultaneous Determination of Short Peptide-Based Drugs in Human Blood Plasma

EN Fisher, ES Melnikov, V Gegeckori, NV Potoldykova… - Molecules, 2022 - mdpi.com
A novel HPLC-ESI-MS/MS method for simultaneous gonadotropin-releasing hormone
(GnRH) analogs and somatostatin analog quantitation was developed and validated. The …

Non-covalent binding tags for batch and flow biocatalysis

RA Rocha, L Esquirol, V Rolland, P Hands… - Enzyme and Microbial …, 2023 - Elsevier
Enzyme immobilization offers considerable advantage for biocatalysis in batch and
continuous flow reactions. However, many currently available immobilization methods …

[HTML][HTML] Targeted mutagenesis of the β-strand DNA binding region of African swine fever virus histone-like protein (pA104R) impairs DNA-binding activity and …

AC Urbano, N Ferreira, N Jordão, F Boinas, C Martins… - Antiviral Research, 2024 - Elsevier
Abstract African Swine Fever (ASF) is a highly contagious disease caused by a double-
stranded DNA virus (ASFV). Despite significant advances made over the last decade, issues …

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8+ T Cell and Antibody Responses

DJ Pattinson, SH Apte, N Wibowo, YP Chuan… - Frontiers in Cellular …, 2019 - frontiersin.org
An effective vaccine against the Plasmodium parasite is likely to require the induction of
robust antibody and T cell responses. Chimeric virus-like particles are an effective vaccine …