Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …

A complex equilibrium of biological signals exists within the human body to regulate normal
cellular function and growth. Unfortunately, there are various ways in which disruption of …

Animal experiments remain essential to understand the fundamental mechanisms
underpinning malignancy and to discover improved methods to prevent, diagnose and treat …

Nasopharyngeal carcinoma (NPC) is known for its high-metastatic potential. Here we report
the identification of the proteoglycan serglycin as a functionally significant regulator of …

Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Accumulating evidence indicates that aged black garlic extract (ABGE) may prove beneficial
in preventing or inhibiting oncogenesis; however, the underlying mechanisms have not …

Background This phase II study assessed the safety and efficacy of everolimus, an oral
mammalian target of rapamycin inhibitor in advanced transitional carcinoma cell (TCC) after …

Chemokine receptors are members of the G protein-coupled receptor superfamily, which
together with chemokine ligands form chemokine networks to regulate various cellular …

Sun C‐H, Chang Y‐H & Pan C‐C (2011) Histopathology58, 1054–1063 Activation of the
PI3K/Akt/mTOR pathway correlates with tumour progression and reduced survival in patients …

Our previous study reported that Epstein–Barr virus (EBV)-encoded latent membrane protein
1 (LMP1) could induce development of CD44+/High stem-like cells in nasopharyngeal …