Current heart valve replacements (HVRs) fail to comprehensively capture the physiological
behavior of native heart valve tissues, allowing the burden of valvular heart disease to …

Heart valve disease is prevalent throughout the world, and the number of heart valve
replacements is expected to increase rapidly in the coming years. Transcatheter heart valve …

Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

The sole effective treatment for most patients with heart valve disease is valve replacement
by implantation of mechanical or biological prostheses. However, mechanical valves …

The importance of experimental setups able to reproduce cardiac functions was well
established in the field of clinical innovations. The mock circulatory loops acquired rising …

The biocompatibility and chemical stability of implantable devices are crucial for their long‐
term success. CarboSil® is a silicon polycarbonate polyurethane copolymer with good …

A series of polycarbonate silicone polyurethanes (SiPCUs) have been synthesized to
develop elastomers with the mechanical properties, biostability, and biocompatibility …

Abstract 3D printing technologies have the potential to revolutionize the manufacture of
heart valves through the ability to create bespoke, complex constructs. In light of recent …

Purpose This study aims to develop a realistic 3D printing-based simulator for the training
and planning of the left atrial appendage occlusion (LAAO) to be used in the cath lab …

Valvular heart diseases (VHDs) have become one of the most prevalent heart diseases
worldwide, and prosthetic valve replacement is one of the effective treatments. With the fast …