Physics and biology of ultrahigh dose-rate (FLASH) radiotherapy: a topical review

N Esplen, MS Mendonca… - Physics in Medicine & …, 2020 - iopscience.iop.org
Ultrahigh dose-rate radiotherapy (RT), or'FLASH'therapy, has gained significant momentum
following various in vivo studies published since 2014 which have demonstrated a reduction …

[HTML][HTML] Radiochromic films for the two-dimensional dose distribution assessment

P Casolaro - Applied Sciences, 2021 - mdpi.com
Radiochromic films are mainly used for two-dimensional dose verification in photon,
electron, and proton therapy treatments. Moreover, the radiochromic film types available …

Experimental set-up for FLASH proton irradiation of small animals using a clinical system

A Patriarca, C Fouillade, M Auger, F Martin… - International Journal of …, 2018 - Elsevier
Purpose Recent in vivo investigations have shown that short pulses of electrons at very high
dose rates (FLASH) are less harmful to healthy tissues but just as efficient as conventional …

Characteristic of EBT-XD and EBT3 radiochromic film dosimetry for photon and proton beams

S Khachonkham, R Dreindl, G Heilemann… - Physics in Medicine …, 2018 - iopscience.iop.org
Recently, a new type of radiochromic film, the EBT-XD film, has been introduced for high
dose radiotherapy. The EBT-XD film contains the same structure as the EBT3 film but has a …

Proton beam dosimetry at ultra‐high dose rates (FLASH): Evaluation of GAFchromic™(EBT3, EBT‐XD) and OrthoChromic (OC‐1) film performances

D Villoing, C Koumeir, A Bongrand, A Guertin… - Medical …, 2022 - Wiley Online Library
Purpose The ARRONAX cyclotron facility offers the possibility to deliver proton beams from
low to ultra‐high dose rates (UHDR). As a good control of the dosimetry is a prerequisite of …

[HTML][HTML] Real-time dosimetry with radiochromic films

P Casolaro, L Campajola, G Breglio, S Buontempo… - Scientific reports, 2019 - nature.com
Radiochromic film dosimetry has been widely employed in most of the applications of
radiation physics for over twenty years. This is due to a number of appealing features of …

Improvements in pencil beam scanning proton therapy dose calculation accuracy in brain tumor cases with a commercial Monte Carlo algorithm

L Widesott, S Lorentini, F Fracchiolla… - Physics in Medicine …, 2018 - iopscience.iop.org
Abstract A commercial Monte Carlo (MC) algorithm (RayStation version 6.0. 024) for the
treatment of brain tumors with pencil beam scanning (PBS) proton therapy is validated and …

Sensitivity correction of fluorescent nuclear track detectors using alpha particles: Determining LET spectra of light ions with enhanced accuracy

ID Muñoz, LN Burigo, T Gehrke, S Brons… - Medical …, 2023 - Wiley Online Library
Background Radiation fields encountered in proton therapy (PT) and ion‐beam therapy
(IBT) are characterized by a variable linear energy transfer (LET), which lead to a variation of …

Experimental validation of 4D log file‐based proton dose reconstruction for interplay assessment considering amplitude‐sorted 4DCTs

S Spautz, A Jakobi, A Meijers, N Peters, S Löck… - Medical …, 2022 - Wiley Online Library
Purpose The unpredictable interplay between dynamic proton therapy delivery and target
motion in the thorax can lead to severe dose distortions. A fraction‐wise four‐dimensional …

Review of technologies and procedures of clinical dosimetry for scanned ion beam radiotherapy

S Giordanengo, L Manganaro, A Vignati - Physica Medica, 2017 - Elsevier
In the last few years, the use of ions in radiation therapy is gaining interest and it is being
considered medically necessary for a growing subset of tumours. Concurrently, the …