Auger electrons for cancer therapy–a review

A Ku, VJ Facca, Z Cai, RM Reilly - EJNMMI radiopharmacy and chemistry, 2019 - Springer
Abstract Background Auger electrons (AEs) are very low energy electrons that are emitted
by radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I …

Advancements in the use of Auger electrons in science and medicine during the period 2015–2019

RW Howell - International journal of radiation biology, 2023 - Taylor & Francis
Auger electrons can be highly radiotoxic when they are used to irradiate specific molecular
sites. This has spurred basic science investigations of their radiobiological effects and …

ICRU Report 98, Stochastic Nature of Radiation Interactions: Microdosimetry

LA Braby, V Conte, M Dingfelder… - Journal of the …, 2023 - journals.sagepub.com
ICRU Report 98, Stochastic Nature of Radiation Interactions: Microdosimetry - LA Braby, V.
Conte, M. Dingfelder, DT Goodhead, LS Pinsky, AB Rosenfeld, T. Sato, AJ Waker, S. Guatelli …

Monte Carlo single-cell dosimetry using Geant4-DNA: the effects of cell nucleus displacement and rotation on cellular S values

R Salim, P Taherparvar - Radiation and Environmental Biophysics, 2019 - Springer
Investigation of biological effects of low-dose ionizing radiation at the (sub-) cellular level,
which is referred to as microdosimetry, remains a major challenge of today's radiobiology …

Validation of the single-event method for low-energy electron transport via stopping power calculations with MCNP

MA Lively, D Perez, BP Uberuaga, X Tang - Radiation Physics and …, 2024 - Elsevier
Monte Carlo simulations of low-energy (< 50 keV) electron transport in matter are essential
for a broad range of application fields. Several Monte Carlo codes have developed …

Radiobiological and dosimetric assessment of DNA-intercalated 99mTc-complexes bearing acridine orange derivatives

A Belchior, S Di Maria, C Fernandes, P Vaz, A Paulo… - EJNMMI research, 2020 - Springer
Background Recently, a new family of 99m Tc (I)-tricarbonyl complexes bearing an acridine
orange (AO) DNA targeting unit and different linkers between the Auger emitter (99m Tc) …

Cellular dosimetry of 197Hg, 197mHg and 111In: comparison of dose deposition and identification of the cell and nuclear membrane as important targets

Z Cai, N Al-Saden, CJ Georgiou… - International Journal of …, 2023 - Taylor & Francis
Purpose To examine the reliability to model cellular S-values for the Auger electron (AE)
emitters, 111In, 197Hg and 197mHg with MCNP6 and their relative dose deposition in …

Microdosimetry modeling with auger emitters in generalized cell geometry

TL Palmer, K Tkacz-Stachowska… - Physics in Medicine …, 2021 - iopscience.iop.org
A microdosimetry model was developed for the prediction of cell viability for irregular non-
spherical cells that were irradiated by low energy, short range Auger electrons. Measured …

Validation of the single-event method for low-energy electron transport via stopping power calculations with

MA Lively, D Perez, BP Uberuaga, X Tang - Radiation Physics and …, 2023 - osti.gov
Monte Carlo simulations of low-energy (< 50 keV) electron transport in matter are essential
for a broad range of application fields. Several Monte Carlo codes have developed …

EGFR and HER2-targeted radioimmunoconjugates for theranostic molecular imaging and Auger electron radioimmunotherapy of breast cancer

VJ Facca - 2024 - search.proquest.com
Overexpression of the human epidermal growth receptor 1 (HER1, EGFR) and 2 (HER2) are
common in breast cancer (BC) and confer a poor prognosis. HER2-targeted pertuzumab …