The role of NMDA receptors in the pathophysiology and treatment of mood disorders
Mood disorders such as major depressive disorder and bipolar disorder are chronic and
recurrent illnesses that cause significant disability and affect approximately 350 million …
recurrent illnesses that cause significant disability and affect approximately 350 million …
The role of NMDA receptors in bipolar disorder: A systematic review
F Weiss, V Caruso, U De Rosa, MF Beatino… - Bipolar …, 2023 - Wiley Online Library
Objectives Glutamatergic transmission and N‐methyl‐D‐aspartate receptors (NMDARs)
have been implicated in the pathophysiology schizophrenic spectrum and major depressive …
have been implicated in the pathophysiology schizophrenic spectrum and major depressive …
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome‐wide association study of both common and …
Attention‐deficit hyperactivity disorder (ADHD) is a complex polygenic disorder. This study
aimed to discover common and rare DNA variants associated with ADHD in a large …
aimed to discover common and rare DNA variants associated with ADHD in a large …
Biological aspects and candidate biomarkers for psychotic bipolar disorder: a systematic review
M Buoli, A Caldiroli, C Cumerlato Melter… - Psychiatry and …, 2016 - Wiley Online Library
Aim We carried out a systematic review of the available literature about potential biomarkers
of psychotic bipolar disorder (BD‐P), a specific subset presenting worse outcome and …
of psychotic bipolar disorder (BD‐P), a specific subset presenting worse outcome and …
[HTML][HTML] Genetic studies on the tripartite glutamate synapse in the pathophysiology and therapeutics of mood disorders
Both bipolar disorder (BD) and major depressive disorder (MDD) have high morbidity and
share a genetic background. Treatment options for these mood disorders are currently …
share a genetic background. Treatment options for these mood disorders are currently …
Genetics of long-term treatment outcome in bipolar disorder
C Fabbri, A Serretti - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
Bipolar disorder (BD) shows one of the strongest genetic predispositions among psychiatric
disorders and the identification of reliable genetic predictors of treatment response could …
disorders and the identification of reliable genetic predictors of treatment response could …
Metabotropic glutamate receptors as emerging research targets in bipolar disorder
CJ Blacker, CP Lewis, MA Frye, M Veldic - Psychiatry Research, 2017 - Elsevier
Glutamatergic dysregulation is implicated in the neuropathology of bipolar disorder (BD).
There is increasing interest in investigating the role of metabotropic glutamate receptors …
There is increasing interest in investigating the role of metabotropic glutamate receptors …
Adaptive evolution and elucidating the potential inhibitor against schizophrenia to target DAOA (G72) isoforms
Schizophrenia (SZ), a chronic mental and heritable disorder characterized by
neurophysiological impairment and neuropsychological abnormalities, is strongly …
neurophysiological impairment and neuropsychological abnormalities, is strongly …
Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder
R Kandaswamy, A McQuillin, SI Sharp… - JAMA …, 2013 - jamanetwork.com
Importance Genetic markers at the gene encoding the metabotropic glutamate receptor 3
(GRM3) showed allelic association with bipolar disorder. Objective To screen the GRM3 …
(GRM3) showed allelic association with bipolar disorder. Objective To screen the GRM3 …
Influence of an Interaction between Lithium Salts and a Functional Polymorphism in SLC1A2 on the History of Illness in Bipolar Disorder
S Dallaspezia, S Poletti, C Lorenzi, A Pirovano… - Molecular diagnosis & …, 2012 - Springer
Background Bipolar disorder (BD) is a recurrent and disabling illness, characterized by
periods of depression and mania. The history of the illness differs widely between patients …
periods of depression and mania. The history of the illness differs widely between patients …