Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope

MK Al-Omari, M Elaarag, RM Al-Zoubi… - Journal of Enzyme …, 2023 - Taylor & Francis
Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical
research due to their exceptional oxophilicity, low toxicity, and unique structure. They are …

[HTML][HTML] Non-destructive monitoring of 3D cell cultures: new technologies and applications

M Cortesi, E Giordano - PeerJ, 2022 - peerj.com
Abstract 3D cell cultures are becoming the new standard for cell-based in vitro research, due
to their higher transferrability toward in vivo biology. The lack of established techniques for …

Boric acid (boron) attenuates AOM-induced colorectal cancer in rats by augmentation of apoptotic and antioxidant mechanisms

AAJ Jabbar, ZZ Alamri, MA Abdulla… - … Trace Element Research, 2024 - Springer
Boric acid (BA) is a naturally occurring weak Lewis acid containing boron, oxygen, and
hydrogen elements that can be found in water, soil, and plants. Because of its numerous …

[HTML][HTML] Plantaricin BM-1 decreases viability of SW480 human colorectal cancer cells by inducing caspase-dependent apoptosis

H Wang, J Jin, X Pang, Z Bian, J Zhu, Y Hao… - Frontiers in …, 2023 - frontiersin.org
Plantaricin BM-1 is a class IIa bacteriocin produced by Lactobacillus plantarum BM-1 that
has significant antimicrobial activity against food-borne bacteria. In this study, a cell …

[HTML][HTML] Redox Mechanisms Underlying the Cytostatic Effects of Boric Acid on Cancer Cells—An Issue Still Open

G Paties Montagner, S Dominici, S Piaggi, A Pompella… - Antioxidants, 2023 - mdpi.com
Boric acid (BA) is the dominant form of boron in plasma, playing a role in different
physiological mechanisms such as cell replication. Toxic effects have been reported, both …

[HTML][HTML] Boric acid exhibits anticancer properties in human endometrial cancer Ishikawa cells

AÇ Gündoğdu, NS Arı, A Höbel, G Şenol, Ö Eldiven… - Cureus, 2023 - ncbi.nlm.nih.gov
Objective This study aims to explore the potential anti-cancer properties of boric acid (BA) in
human endometrial cancer Ishikawa cells by assessing its influence on cell viability …

[HTML][HTML] Advances in research of biological functions of Isthmin-1

L Menghuan, Y Yang, M Qianhe, Z Na… - Journal of Cell …, 2023 - Springer
Abstract Isthmin-1 (ISM1) was initially thought to be a brain secretory factor, but with the
development of technical means of research and the refinement of animal models …

Boric acid affects cell proliferation, apoptosis, and oxidative stress in ALL cells

B Hilal, A Eldem, T Oz, M Pehlivan, I Pirim - Biological Trace Element …, 2023 - Springer
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia from
early T-cell progenitors. Interest grows in creating less toxic agents and therapies for chemo …

Boric acid alters the expression of DNA double break repair genes in MCF-7-derived breast cancer stem cells

TS Sevimli, A Ghorbani, F Gakhiyeva… - … Trace Element Research, 2023 - Springer
Breast cancer pathology ranks second in mortality among women worldwide due to the
resistance of cancer stem cells in tumor tissue to radiotherapy and chemotherapy and their …

[HTML][HTML] In Vitro Effects of Boric Acid on Cell Cycle, Apoptosis, and miRNAs in Medullary Thyroid Cancer Cells

O Yıldırım, M Seçme, Y Dodurga, GA Mete… - … Trace Element Research, 2024 - Springer
Medullary thyroid cancer (MTC) is a highly aggressive and chemotherapy-resistant cancer
originating from the thyroid's parafollicular C cells. Due to its resistance to conventional …