[HTML][HTML] Anti-depressant properties of crocin molecules in saffron

SA Siddiqui, A Ali Redha, ER Snoeck, S Singh… - Molecules, 2022 - mdpi.com
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with
therapeutic effects. It has been described in pharmacopoeias to be variously acting …

Phytochemistry, pharmacology, and potential clinical applications of saffron: A review

B Xing, S Li, J Yang, D Lin, Y Feng, J Lu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Saffron, the dried red stigma of the perennial herb Crocus
sativus L.(Iridaceae), is one of the most important and expensive spices in the world. It is …

Mechanism involved in insulin resistance via accumulation of β-amyloid and neurofibrillary tangles: Link between type 2 diabetes and Alzheimer's disease

SK Rad, A Arya, H Karimian, P Madhavan… - Drug design …, 2018 - Taylor & Francis
The pathophysiological link between type 2 diabetes mellitus (T2DM) and Alzheimer's
disease (AD) has been suggested in several reports. Few findings suggest that T2DM has …

Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome

D Bagetta, A Maruca, A Lupia, F Mesiti… - European Journal of …, 2020 - Elsevier
Alteration of nutritional habits play an essential role on the risk of developing Metabolic
Syndrome (MetS). Several epidemiological studies have shown that assuming diets rich of …

Bioactives in spices, and spice oleoresins: Phytochemicals and their beneficial effects in food preservation and health promotion

F Shahidi, A Hossain - Journal of Food Bioactives, 2018 - isnff-jfb.com
Spices have broadly been used as food flavoring and folk medicine since ancient times.
Numerous phytochemicals have been identified in spices, namely thymol (ajowan and …

Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats

HO Abou-Hany, H Atef, E Said, HA Elkashef… - Chemico-biological …, 2018 - Elsevier
Diabetic Nephropathy (DN) is one of the main complications associated with diabetes
mellitus. Persistently elevated blood glucose level drives histopathological changes in renal …

Herbal Medicines Targeting the Improved β‐Cell Functions and β‐Cell Regeneration for the Management of Diabetes Mellitus

ASD Wickramasinghe, P Kalansuriya… - Evidence‐Based …, 2021 - Wiley Online Library
There is an increasing trend of investigating natural bioactive compounds targeting
pancreatic β‐cells for the prevention/treatment of diabetes mellitus (DM). With the …

[HTML][HTML] Exercise medicine for cancer cachexia: Targeted exercise to counteract mechanisms and treatment side effects

G Mavropalias, M Sim, DR Taaffe, DA Galvão… - Journal of Cancer …, 2022 - Springer
Purpose Cancer-induced muscle wasting (ie, cancer cachexia, CC) is a common and
devastating syndrome that results in the death of more than 1 in 5 patients. Although …

Antidiabetic potential of saffron and its active constituents

H Yaribeygi, V Zare, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
The prevalence of diabetes mellitus is growing rapidly worldwide. This metabolic disorder
affects many physiological pathways and is a key underlying cause of a multitude of …

Therapeutic potential of saffron in brain disorders: From bench to bedside

E Bej, AR Volpe, P Cesare, A Cimini… - Phytotherapy …, 2024 - Wiley Online Library
Saffron is a spice derived from the flower of Crocus sativus L., which has been used for
centuries as a coloring and flavoring agent, as well as a source of medicinal compounds …