Glycans are among the most important cell molecular components. However, given their
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …

There is a large global unmet need for the development of countermeasures to combat
hundreds of viruses known to cause human disease and for the establishment of a …

Background Despite clinical success with anti-spike vaccines, the effectiveness of
neutralizing antibodies and vaccines has been compromised by rapidly spreading SARS …

Studying viral–host protein–protein interactions can facilitate the discovery of therapies for
viral infection. We use high-throughput yeast two-hybrid experiments and mass spectrometry …

Abstract The Chinese tree shrew (Tupaia belangeri chinensis) is emerging as an important
experimental animal in multiple fields of biomedical research. Comprehensive reference …

Cancer immunotherapy, including the inhibition of immune checkpoints, improves the tumor
immune microenvironment and is an effective tool for cancer therapy. More effective and …

Individuals with metabolic dysregulation of cellular glycosylation often experience severe
influenza disease, with a poor immune response to the virus and low vaccine efficacy. Here …

Over the past 60 years, more than 100 antiviral drugs or their combinations have been
approved for clinical use. Antiviral drugs can be classified according to their chemical nature …

Autograft has long been the gold standard for various bone surgeries. Nevertheless, the
increasing usage of synthetic implants is taking over the operation rooms due to biosafety …

Glycosylation inhibition has great potential in cancer treatment. However, the corresponding
cellular response, protein expression and glycosylation changes remain unclear. As a cell …