Acromegaly is a chronic systemic disease with many complications and is associated with increased mortality when not adequately treated. Substantial advances in acromegaly …
L Katznelson, ER Laws Jr, S Melmed… - The Journal of …, 2014 - academic.oup.com
Objective: The aim was to formulate clinical practice guidelines for acromegaly. Participants: The Task Force included a chair selected by the Endocrine Society Clinical Guidelines …
S Melmed - New England Journal of Medicine, 2006 - Mass Medical Soc
Pituitary tumors account for about 15% of primary intracranial neoplasms. Proliferation of pituitary cells, which secrete hormones, may result in a spectrum of endocrine symptoms …
S Melmed, FF Casanueva, A Klibanski, MD Bronstein… - Pituitary, 2013 - Springer
Abstract In March 2011, the Acromegaly Consensus Group met to revise and update the guidelines on the diagnosis and treatment of acromegaly complications. The meeting was …
AACE= American Association of Clinical Endocrinologists; BEL=“best evidence” level; BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …
OM Dekkers, NR Biermasz, AM Pereira… - The Journal of …, 2008 - academic.oup.com
Context: Several studies have assessed mortality risk in patients treated for acromegaly. All studies found a mortality that was higher than expected for the general population, but most …
A Colao, LFS Grasso, A Giustina, S Melmed… - Nature Reviews …, 2019 - nature.com
Acromegaly is characterized by increased release of growth hormone and, consequently, insulin-like growth factor I (IGF1), most often by a pituitary adenoma. Prolonged exposure to …
C Capatina, JAH Wass - Journal of Endocrinology, 2015 - joe.bioscientifica.com
Acromegaly (ACM) is a chronic, progressive disorder caused by the persistent hypersecretion of GH, in the vast majority of cases secreted by a pituitary adenoma. The …
Purpose Pituitary adenomas give rise to physical and psychological symptoms, which may persist after biochemical cure. Growing attention has been paid to quality of life (QoL) in …