The nucleotide-binding, oligomerization domain-like receptor family pyrin domain containing
3 (NLRP3) inflammasome is a multiprotein complex that combines sensing, regulation, and …

Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …

Traumatic brain injury (TBI) and Alzheimer's disease (AD) represent 2 of the largest sources
of death and disability in the United States. Recent studies have identified TBI as a potential …

Inflammasomes are multimeric protein complexes that can sense a plethora of microbe‐and
damage‐associated molecular signals. They play important roles in innate immunity and are …

Stem cell-based treatments have been suggested as promising candidates for stroke.
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …

Inflammasomes are cytoplasmic inflammatory signaling protein complexes that detect
microbial materials, sterile inflammatory insults, and certain host-derived elements …

Traumatic brain injury (TBI) is still a major cause of concern for public health, and out of all
the trauma‐related injuries, it makes the highest contribution to death and disability …

Brain degenerative disorders such as Alzheimer's disease (AD) can be exacerbated by
aberrant metabolism. Supplementation with probiotic bacteria is emerging as a promising …

Fibrillar aggregates and soluble oligomers of both Amyloid-β peptides (Aβs) and
hyperphosphorylated Tau proteins (p-Tau-es), as well as a chronic neuroinflammation are …

Significance: Inflammasomes are multimeric complexes that, as part of the innate immune
response, sense a wide range of pathogenic and sterile stimuli. They consist of three …