Near infrared spectroscopy (NIRS) is a powerful noninvasive tool with which to study the
matching of oxygen delivery to oxygen utilization and the number of new publications …

In most daily activities related to work or leisure, the energy for muscle work substantially
comes from oxidative metabolism. Functional limitations or impairments of this metabolism …

Muscular exercise requires transitions to and from metabolic rates often exceeding an order
of magnitude above resting and places prodigious demands on the oxidative machinery and …

Pharmacological sodium nitrate supplementation has been reported to reduce the O 2 cost
of submaximal exercise in humans. In this study, we hypothesized that dietary …

The purpose of this study was to elucidate the mechanistic bases for the reported reduction
in the O2 cost of exercise following short-term dietary nitrate (NO3−) supplementation. In a …

In the last decade the study of the human brain and muscle energetics underwent a radical
change, thanks to the progressive introduction of noninvasive techniques, including near …

Peripheral arterial disease (PAD) results in a failure to adequately supply blood and oxygen
(O2) to working tissues and presents as claudication pain during walking. Nitric oxide (NO) …

The purpose of this study was to compare the effects of l-citrulline (Cit) and l-arginine (Arg)
supplementation on nitric oxide (NO) biomarkers, pulmonary O 2 uptake (V̇ o 2) kinetics …

Severe‐intensity constant‐work‐rate exercise results in the attainment of maximal oxygen
uptake, but the muscle metabolic milieu at the limit of tolerance (Tlim) for such exercise …

The activities of daily living typically occur at metabolic rates below the maximum rate of
aerobic energy production. Such activity is characteristic of the nonsteady state, where …