Substance use disorders (SUDs) are highly prevalent. SUDs involve vicious cycles of binges
followed by occasional periods of abstinence with recurrent relapses despite treatment and …

Depression is a common, devastating illness. Due to complicated causes and limited
treatments, depression is still a major problem that plagues the world. Silent information …

Obesity is associated with a high prevalence of mood disorders such as anxiety and
depression. Both stress and high fat diet can alter the gut microbiota and contribute to …

Epigenetic modifications are emerging as major players in the pathogenesis of
neurodegenerative disorders and susceptibility to acute brain injury. DNA and histone …

Mental disorders including depression, anxiety, schizophrenia, autism spectrum disorders,
bipolar and etc. have a considerable proportion of global disorder burden. Many nutritional …

Based on the findings in recent years, we summarize the therapeutic potential of vorinostat
(VOR), the first approved histone deacetylase (HDAC) inhibitor, in disorders of brain, and …

Social determinants of health (SDoH) impact health and wellness. The link between SDoH
and adverse health outcomes, including symptom occurrence and severity, may be …

Interest in adolescence as a crucial stage of neurobehavioral maturation is growing, as is
the concern of how stress may perturb this critical period of development. Though it is well …

Abstract Background Long non-coding RNAs (lncRNAs) have close relationships with
oxidative stress, nutritional deficiency, DNA damage and other types of cellular stress …

The full epigenetic repertoire governing breast cancer metastasis is not completely
understood. Here, we discuss the histone methyltransferase SET Domain Bifurcated Histone …