The value of reference genomes in the conservation of threatened species
Conservation initiatives are now more crucial than ever—over a million plant and animal
species are at risk of extinction over the coming decades. The genetic management of …
species are at risk of extinction over the coming decades. The genetic management of …
Perspective: Genome resource banking for wildlife conservation: Promises and caveats
WV Holt, P Comizzoli - CryoLetters, 2021 - ingentaconnect.com
The value of cryopreserved germplasm in agriculture, aquaculture and medicine was
recognized in the mid-twentieth century following the discovery in the late 1940s of a method …
recognized in the mid-twentieth century following the discovery in the late 1940s of a method …
The evolution of two transmissible cancers in Tasmanian devils
Tasmanian devils have spawned two transmissible cancer lineages, named devil facial
tumor 1 (DFT1) and devil facial tumor 2 (DFT2). We investigated the genetic diversity and …
tumor 1 (DFT1) and devil facial tumor 2 (DFT2). We investigated the genetic diversity and …
A demonstration of conservation genomics for threatened species management
BR Wright, KA Farquharson… - Molecular Ecology …, 2020 - Wiley Online Library
As species extinction rates increase, genomics provides a powerful tool to support intensive
management of threatened species. We use the Tasmanian devil (Sarcophilus harrisii) to …
management of threatened species. We use the Tasmanian devil (Sarcophilus harrisii) to …
Conserving adaptive potential: lessons from Tasmanian devils and their transmissible cancer
Maintenance of adaptive genetic variation has long been a goal of management of natural
populations, but only recently have genomic tools allowed identification of specific loci …
populations, but only recently have genomic tools allowed identification of specific loci …
Population bottlenecks constrain host microbiome diversity and genetic variation impeding fitness
M Ørsted, E Yashiro, AA Hoffmann… - PLoS Genetics, 2022 - journals.plos.org
It is becoming increasingly clear that microbial symbionts influence key aspects of their
host's fitness, and vice versa. This may fundamentally change our thinking about how …
host's fitness, and vice versa. This may fundamentally change our thinking about how …
A genomic framework to assist conservation breeding and translocation success: A case study of a critically endangered turtle
HV Nelson, KA Farquharson, A Georges… - … Science and Practice, 2024 - Wiley Online Library
Conservation breeding programs are an effective approach to addressing biodiversity loss.
Captive populations are managed to maintain genetic diversity, yet there remains an …
Captive populations are managed to maintain genetic diversity, yet there remains an …
Assessing evolutionary processes over time in a conservation breeding program: A combined approach using molecular data, simulations and pedigree analysis
Captive breeding for conservation is widely used to prevent extinction, however these
programs face many challenges due to small population size, founder effects, lack of …
programs face many challenges due to small population size, founder effects, lack of …
Contemporary and historical selection in Tasmanian devils (Sarcophilus harrisii) support novel, polygenic response to transmissible cancer
AR Stahlke, B Epstein, S Barbosa… - … of the Royal …, 2021 - royalsocietypublishing.org
Tasmanian devils (Sarcophilus harrisii) are evolving in response to a unique transmissible
cancer, devil facial tumour disease (DFTD), first described in 1996. Persistence of wild …
cancer, devil facial tumour disease (DFTD), first described in 1996. Persistence of wild …
First evidence of deviation from Mendelian proportions in a conservation programme
Classic Mendelian inheritance is the bedrock of population genetics and underpins
pedigree‐based management of animal populations. However, assumptions of Mendelian …
pedigree‐based management of animal populations. However, assumptions of Mendelian …