The complexity of cardiovascular responses produced by 5-hydroxytryptamine (5-HT,
serotonin), including bradycardia or tachycardia, hypotension or hypertension, and …

5-Hydroxytryptamine (5-HT), or serotonin, plays a crucial role as a neuromodulator and/or
neurotransmitter of several nervous system functions. Its actions are complex, and depend …

Background—Cardiac ganglia were originally thought to contain only cholinergic neurons
relaying parasympathetic information from preganglionic brain stem neurons to the heart …

Vasovagal syncope is a common disorder that can compromise quality of life and lead to
significant morbidity. It is characterized by an initial exaggerated sympathetic output followed …

Decreased resting vagal (parasympathetic) tone is implicated in the development of stress-
related disorders, including anxiety and depression. Chronic stress elevates the expression …

The acute cardiovascular and respiratory responses of the gulf toadfish, Opsanus beta, to
acute hypoxia or exposure to the O2 chemoreceptor stimulant, sodium cyanide (NaCN) were …

This study investigated whether granisetron, a 5‐HT3 receptor antagonist, can alter the
Bezold‐Jarisch reflex (ie, hypotension and inappropriate heart rate slowing). A hemorrhagic …

HT inhibits cardiac sympathetic neurotransmission in normoglycaemic rats, via 5-HT1B, 5-
HT1D and 5-HT5A receptor activation. Since type 1 diabetes impairs the cardiac …

A single nucleotide polymorphism in the serotonin 2A receptor gene (HTR2A rs6311
guanine [G] vs. adenine [A]) appears associated with positive emotional contagion (social …

Neurally mediated hypotension is a common clinical problem that can be diagnosed by
head-up tilt (HUT) table testing. 1–3 In patients with neurally mediated syncope, sympathetic …