Isolated transition metal clusters have been established as useful models for extended metal
surfaces or deposited metal particles, to improve the understanding of their surface …

Traditional Chinese medicine (TCM) has been an indispensable source of drugs for curing
various human diseases. However, the inherent chemical diversity and complexity of TCM …

(MS) and MS-driven proteomics have continued to develop as the premier tools for
characterizing proteome composition, structure, and function. 2 The new era of proteomics …

Controlling the chemical glycosylation reaction remains the major challenge in the synthesis
of oligosaccharides. Though 1, 2-trans glycosidic linkages can be installed using …

Sulfur is one of six life-essential elements, but its path from interstellar clouds to planets and
their atmospheres is not well known. Astronomical observations in dense clouds have so far …

Background Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an inborn error of lysine
catabolism that presents with refractory epilepsy in newborns. Biallelic ALDH7A1 variants …

Modern untargeted mass spectrometry (MS) analyses quickly detect and resolve thousands
of molecular compounds. Although features are readily annotated with a molecular formula …

Combining the individual analytical strengths of mass spectrometry and infrared
spectroscopy, infrared ion spectroscopy is increasingly recognized as a powerful tool for …

Glycosyl cations are crucial intermediates formed during enzymatic and chemical
glycosylation. The intrinsic high reactivity and short lifetime of these reaction intermediates …

Infrared ion spectroscopy (IRIS) requires reproducibility and standard protocols in order to
be fully appreciated as an analytical tool. An important parameter in IRIS measurements is …