Acanthamoeba and its pathogenic role in granulomatous amebic encephalitis

SK Kalra, P Sharma, K Shyam, N Tejan… - Experimental …, 2020 - Elsevier
Acanthamoeba is a free-living amoeba that is widely distributed in the environment. It is an
opportunist protist, which is known to cause rare yet fatal infection of the central nervous …

Immunopathogenicity of Acanthamoeba spp. in the Brain and Lungs

K Kot, N Łanocha-Arendarczyk… - International Journal of …, 2021 - mdpi.com
Free-living amoebas, including Acanthamoeba spp., are widely distributed in soil, water, and
air. They are capable of causing granulomatous amebic encephalitis, Acanthamoeba …

Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes

L Ferrins, MJ Buskes, MM Kapteyn, HN Engels… - Frontiers in …, 2023 - frontiersin.org
Acanthamoeba species, Naegleria fowleri, and Balamuthia mandrillaris are opportunistic
pathogens that cause a range of brain, skin, eye, and disseminated diseases in humans and …

Microbiological diagnosis of Acanthamoebic keratitis: Experience from tertiary care center of North India

K Megha, M Sharma, A Gupta, R Sehgal… - … and Infectious Disease, 2021 - Elsevier
Acanthamoeba keratitis (AK) is a painful vision-threatening infection caused by pathogenic
free-living Acanthamoeba. Due to the non-specific clinical presentation, this condition tends …

Evaluation of in vitro activity of five antimicrobial agents on Acanthamoeba isolates and their toxicity on human corneal epithelium

K Megha, M Sharma, C Sharma, A Gupta, R Sehgal… - Eye, 2022 - nature.com
Background Acanthamoeba keratitis (AK) is an important cause of ocular morbidity in both
contact lens wearers and non wearers. Medical management comprises prolonged empiric …

Molecular detection of Acanthamoeba spp. in Seven Crater Lakes of Laguna, Philippines

LD Ballares, FR Masangkay, J Dionisio… - Journal of Water and …, 2020 - iwaponline.com
HIGHLIGHTS This study is the first to provide data on the presence of Acanthamoeba spp.
on the surface waters of the Seven Crater Lakes of Laguna, Philippines. High prevalence of …

Sub-Genotyping of Acanthamoeba T4 Complex: Experience from North India

K Megha, M Sharma, A Gupta, R Sehgal, S Khurana - Parasitologia, 2023 - mdpi.com
The Acanthamoeba genus comprises the free-living amoebae that are ubiquitously present
as opportunistic pathogens. They cause serious human diseases—for instance …

Assessment of pathogenic potential of Acanthamoeba isolates by in vitro and in vivo tests

C Sharma, S Khurana, K Megha, A Thakur… - Parasitology …, 2023 - Springer
Acanthamoeba are free-living protozoa present ubiquitously in numerous environmental
reservoirs that exist as an actively feeding trophozoite or a dormant cyst stage. The …

[PDF][PDF] Central nervous system infections caused by pathogenic free-living amoebae: An Indian perspective

R Raju, S Khurana, A Mahadevan, DV John - Trop. Biomed, 2022 - scholar.archive.org
Pathogenic free-living amoebae (FLA), namely Acanthamoeba sp., Naegleria fowleri and
Balamuthia mandrillaris are distributed worldwide. These neurotropic amoebae can cause …

Molecular diagnosis of encephalitis/meningoencephalitis caused by Free-Living Amoebae from a tertiary center in India

S Khurana, C Sharma, BD Radotra, A Mewara… - Pathogens, 2022 - mdpi.com
Background: Pathogenic free-living amoeba (FLA) such as Acanthamoeba spp., Naegleria
fowleri, and Balamuthia mandrillaris are causative agents of fatal amoebic encephalitis …