Depression is a major contributor to healthcare costs and is projected to be the leading
cause of disease burden in middle and higher income countries by the year 2030. w1 …

Background The prevalence of treatment-resistant geriatric depression (GD) highlights the
need for treatments that preserve cognitive functions and recognize polypharmacy in elderly …

BACKGROUND: Whether course trajectories of depressive and anxiety disorders are
different, remains an important question for clinical practice and informs future psychiatric …

BACKGROUND: The Geriatric Depression Scale (GDS) has been evaluated in hospital
settings but its validity and added value in primary care is uncertain. We therefore conducted …

Background Despite their high rates of depression, homebound older adults have limited
access to evidence‐based psychotherapy. The purpose of this paper was to report both …

Background This study aimed to identify patient characteristics associated with poor
outcomes in psychological therapy, and to develop a patient profiling method. Method …

Objective: Some cases are thought to be more complex and difficult to treat, although there
is little consensus on how to define complexity in psychological care. This study proposes an …

Purpose To examine the natural course and outcome of major depressive disorder (MDD) in
primary care over 39 months. Methods Prospective cohort study of 1,338 consecutive …

Objective: Insomnia and major depressive disorders (MDD) often co-occur, and such
comorbidity has been associated with poorer outcomes for both conditions. However …

Objective Depression among older adults is associated with both disability and somatic
disease. We aimed to further understand this complicated relationship and to study the …