[HTML][HTML] Tumour-associated macrophages: versatile players in the tumour microenvironment

ZZ Ji, MKK Chan, ASW Chan, KT Leung… - Frontiers in Cell and …, 2023 - ncbi.nlm.nih.gov
Abstract Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the
tumour microenvironment. Their roles in the cancer immunity are complicated, both pro …

[HTML][HTML] Tumors of the nervous system and hearing loss: beyond vestibular schwannomas

C Ruiz-García, L Lassaletta, P López-Larrubia… - Hearing Research, 2024 - Elsevier
Hearing loss is a common side effect of many tumor treatments. However, hearing loss can
also occur as a direct result of certain tumors of the nervous system, the most common of …

[HTML][HTML] Single-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets

P Baruah, C Mahony, JL Marshall, CG Smith… - British Journal of …, 2024 - nature.com
Abstract Background Vestibular schwannomas (VSs) remain a challenge due to their
anatomical location and propensity to growth. Macrophages are present in VS but their roles …

The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma

GE Gregory, AP Jones, MJ Haley, C Hoyle… - Brain …, 2023 - academic.oup.com
Bilateral vestibular schwannoma is the hallmark of NF2-related schwannomatosis, a rare
tumour predisposition syndrome associated with a lifetime of surgical interventions …

[HTML][HTML] Targeted STAT1 therapy for LZTR1‐driven peripheral nerve sheath tumor

T Ivanisevic, M Steklov, B Lechat… - Cancer …, 2023 - ncbi.nlm.nih.gov
Dear Editor, Schwannomas are peripheral nervous system tumors that cause chronic pain,
numbness, and potentially lifethreatening organ dysfunction. Surgery is a conventional …

Evidence for inflammation in normal appearing brain regions in patients with growing sporadic vestibular schwannoma: a PET study

B Alfaifi, R Hinz, A Jackson, A Wadeson… - Neuro-Oncology …, 2024 - academic.oup.com
Background Non-auditory symptoms can be a prominent feature in patients with sporadic
vestibular schwannoma (VS), but the cause of these symptoms is unknown. Inflammation is …

Cytokine Profiling of Cyst Fluid and Tumor-Associated Macrophages in Cystic Vestibular Schwannoma

E Nisenbaum, M Wiefels, J Telischi… - Otology & …, 2023 - journals.lww.com
Background The vestibular schwannoma (VS) secretome can initiate monocyte recruitment
and macrophage polarization to M1 (proinflammatory) and/or M2 (protumorigenic) …

High-Dimensional Imaging of Vestibular Schwannoma Reveals Distinctive Immunological Networks Across Histomorphic Niches in NF2-related Schwannomatosis

AP Jones, MJ Haley, GE Gregory, CJ Hannan… - bioRxiv, 2024 - biorxiv.org
NF2-related Schwannomatosis (NF2 SWN) is a rare tumour-predisposition syndrome
characterised by the growth of multiple central and peripheral nervous system neoplasms …