Biological and taxonomic perspective of triterpenoid glycosides of sea cucumbers of the family Holothuriidae (Echinodermata, Holothuroidea)

M Honey-Escandón, R Arreguín-Espinosa… - … and Physiology Part B …, 2015 - Elsevier
Since the discovery of saponins in sea cucumbers, more than 150 triterpene glycosides
have been described for the class Holothuroidea. The family Holothuriidae has been …

[PDF][PDF] Chemical biodiversity and bioactivities of Saponins in Echinodermata with an emphasis on sea cucumbers (Holothuroidea)

E Kamyab, MY Kellermann, A Kunzmann… - YOUMARES 9-the …, 2020 - library.oapen.org
Echinoderms are a source of a broad range of secondary metabolites with a large variety of
bioactive properties. Although pigment and lipid derivatives are the major groups of …

Anti-proliferative and anti-inflammatory activities of the sea cucumber Holothuria polii aqueous extract

M Kareh, R El Nahas, L Al-Aaraj… - SAGE Open …, 2018 - journals.sagepub.com
Objective: Sea cucumbers are considered among the most important functional foods.
Following bioassay guided fractionation, we assessed the anti-proliferative and anti …

Bioactive compounds of sea cucumbers and their therapeutic effects

S Shi, W Feng, S Hu, S Liang, N An, Y Mao - Chinese Journal of …, 2016 - Springer
Sea cucumbers belong to the Class Holothuroidea of marine invertebrates. They are
commercially valuable and prized as a food and folk medicine in Asia. Nutritionally, sea …

[HTML][HTML] EDBD—3,6-Epidioxy-1,10-Bisaboladiene—An Endoperoxide Sesquiterpene Obtained from Drimys brasiliensis (Winteraceae) Exhibited Potent Preclinical Efficacy …

E Umehara, TR Teixeira, RA Cajás, MC Amaro… - Antibiotics, 2024 - mdpi.com
Schistosomiasis, a neglected tropical disease impacting over 250 million individuals
globally, remains a major public health challenge due to its prevalence and significant …

Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni

J Kellershohn, L Thomas, SR Hahnel… - PLoS Neglected …, 2019 - journals.plos.org
Natural products have moved into the spotlight as possible sources for new drugs in the
treatment of helminth infections including schistosomiasis. Surprisingly, insect-derived …

Identification of echinoderm metabolites as potential inhibitors targeting wild-type and mutant forms of Escherichia coli RNA polymerase (RpoB) for tuberculosis …

FM Alsulais, BA Alhaidhal, RA Mothana, AR Alanzi - Plos one, 2024 - journals.plos.org
Tuberculosis (TB) remains a critical global health challenge, with the emergence of drug-
resistant strains heightening concerns. The development of effective drugs targeting both …

A novel antitumor compound nobiliside D isolated from sea cucumber (Holothuria nobilis Selenka)

JJ Zhang, KQ Zhu - Experimental and Therapeutic …, 2017 - spandidos-publications.com
An anticancer compound, triterpene glycoside, was isolated from Holothuria nobilis Selenka.
Its chemical structure and configuration were determined by two‑dimensional nuclear …

A potential therapeutic effect of sea cucumber Holothuria polii extract during the intestinal phase of experimental trichinellosis

SA El-Saidy, AS El-Feki, GM El-Khodary… - Journal of Parasitic …, 2024 - Springer
Trichinellosis is a severe parasitic disease transmitted by food, specifically caused by
Trichinella spiralis, which exhibits great clinical importance worldwide. Albendazole (ABZ) is …

Structure elucidation, protein profile and the antitumor effect of the biological active substance extracted from sea cucumber Holothuria polii

NEE Omran, AM Khedr - Toxicology and industrial health, 2015 - journals.sagepub.com
Holothuria polii (Delle Chiaje, 1823)(Holothuriidae) is a sea cucumber inhabiting
Mediterranean Sea coast of Egypt. The bioactive compound of its tegument has antifungal …