Tumor microenvironment enriches the stemness features: the architectural event of therapy resistance and metastasis

P Nallasamy, RK Nimmakayala, S Parte, AC Are… - Molecular cancer, 2022 - Springer
Cancer divergence has many facets other than being considered a genetic term. It is a
tremendous challenge to understand the metastasis and therapy response in cancer …

Targeting breast cancer stem cells to overcome treatment resistance

S Palomeras, S Ruiz-Martínez, T Puig - Molecules, 2018 - mdpi.com
Despite advances in breast cancer diagnosis and treatment, many patients still fail therapy,
resulting in disease progression, recurrence, and reduced overall survival. Historically …

Breast cancer stem cells: Features, key drivers and treatment options

J Dittmer - Seminars in cancer biology, 2018 - Elsevier
The current view is that breast cancer is a stem cell disease characterized by the existence
of cancer cells with stem-like features and tumor-initiating potential. These cells are made …

AIE-active theranostic system: selective staining and killing of cancer cells

C Gui, E Zhao, RTK Kwok, ACS Leung, JWY Lam… - Chemical …, 2017 - pubs.rsc.org
Cancer is the leading cause of death worldwide. With the advantages of low cost, high
sensitivity and ease of accessibility, fluorescence imaging has been widely used for cancer …

Recent advances in microtubule-stabilizing agents

YN Cao, LL Zheng, D Wang, XX Liang, F Gao… - European journal of …, 2018 - Elsevier
Highly dynamic mitotic spindle microtubules are superb therapeutic targets for a group of
chemically diverse and clinically successful anticancer drugs. Microtubule-targeted drugs …

Breast cancer stem cells: biomarkers, identification and isolation methods, regulating mechanisms, cellular origin, and beyond

X Zhang, K Powell, L Li - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer stem cells are blamed to be responsible for breast cancer
tumorigenesis, metastasis, drug resistance and tumor recurrence. Therefore, it is critical to …

Therapeutic strategies targeting cancer stem cells and their microenvironment

HR Sun, S Wang, SC Yan, Y Zhang, PJ Nelson… - Frontiers in …, 2019 - frontiersin.org
Cancer stem cells (CSCs) have been demonstrated in a variety of tumors and are thought to
act as a clonogenic core for the genesis of new tumor growth. This small subpopulation of …

Mitochondria-targetable carbon quantum dots for differentiating cancerous cells from normal cells

G Gao, YW Jiang, J Yang, FG Wu - Nanoscale, 2017 - pubs.rsc.org
In this study, a series of fluorescent carbon quantum dots (or carbon dots, CDs) with inherent
mitochondrial targeting/imaging and cancerous/normal cell differentiation capabilities were …

Targeting breast cancer stem cells through retinoids: a new hope for treatment

N Jan, S Sofi, H Qayoom, BU Haq, A Shabir… - Critical Reviews in …, 2023 - Elsevier
Breast cancer is a complex and diverse disease accounting for nearly 30% of all cancers
diagnosed in females. But unfortunately, patients develop resistance to the existing …

Advances in Monoclonal Antibody Therapies for Triple-Negative Breast Cancer: Immunotherapeutic and Targeted Strategies

A Khalaji, S Hadad, J Sarmadian… - Current Molecular …, 2025 - ingentaconnect.com
Triple-negative breast cancer (TNBC) presents considerable obstacles because of its highly
aggressive characteristics and limited availability of specific therapeutic interventions. The …