Harnessing mosquito–Wolbachia symbiosis for vector and disease control

K Bourtzis, SL Dobson, Z Xi, JL Rasgon, M Calvitti… - Acta tropica, 2014 - Elsevier
Mosquito species, members of the genera Aedes, Anopheles and Culex, are the major
vectors of human pathogens including protozoa (Plasmodium sp.), filariae and of a variety of …

Molecular mechanisms of white spot syndrome virus infection and perspectives on treatments

B Verbruggen, LK Bickley, R Van Aerle, KS Bateman… - Viruses, 2016 - mdpi.com
Since its emergence in the 1990s, White Spot Disease (WSD) has had major economic and
societal impact in the crustacean aquaculture sector. Over the years shrimp farming alone …

Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains

J Martinez, B Longdon, S Bauer, YS Chan… - PLoS …, 2014 - journals.plos.org
In the last decade, bacterial symbionts have been shown to play an important role in
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …

The microbiome modulates arbovirus transmission in mosquitoes

S Hegde, JL Rasgon, GL Hughes - Current opinion in virology, 2015 - Elsevier
Highlights•Complex interactions occur within the mosquito holobiome that profoundly alter
the phenotype of the host.•Bacteria can enhance or suppress arbovirus transmission in …

MicroRNA functions in insects

S Asgari - Insect biochemistry and molecular biology, 2013 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and
viruses. Their role as master regulators of gene expression in various biological processes …

A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies

ST Ogunlade, MT Meehan, AI Adekunle, DP Rojas… - Vaccines, 2021 - mdpi.com
Arthropod-borne viruses (Arboviruses) continue to generate significant health and economic
burdens for people living in endemic regions. Of these viruses, some of the most important …

Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti

G Zhang, M Hussain, SL O'Neill… - Proceedings of the …, 2013 - National Acad Sciences
The endosymbiont Wolbachia is common among insects and known for the reproductive
manipulations it exerts on hosts as well as inhibition of virus replication in their hosts …

The Native Wolbachia Symbionts Limit Transmission of Dengue Virus in Aedes albopictus

L Mousson, K Zouache, C Arias-Goeta… - PLoS neglected …, 2012 - journals.plos.org
Background The chikungunya (CHIK) outbreak that struck La Reunion Island in 2005 was
preceded by few human cases of Dengue (DEN), but which surprisingly did not lead to an …

West Nile virus encodes a microRNA-like small RNA in the 3′ untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells

M Hussain, S Torres, E Schnettler, A Funk… - Nucleic acids …, 2012 - academic.oup.com
West Nile virus (WNV) belongs to a group of medically important single-stranded, positive-
sense RNA viruses causing deadly disease outbreaks around the world. The 3 …

[HTML][HTML] Lessons from studying insect symbioses

AE Douglas - Cell host & microbe, 2011 - cell.com
As in mammals, insect health is strongly influenced by the composition and activities of
resident microorganisms. However, the microbiota of insects is generally less diverse than …