Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …
Progress of Metal‐Based Anticancer Chemotherapeutic Agents in Last two Decades and their Comprehensive Biological (DNA/RNA Binding, Cleavage and …
F Arjmand, H Yasir Khan, S Tabassum - The Chemical Record, 2023 - Wiley Online Library
During last two decades, there has been an enormous growth in the discovery of innovative
active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro‐molar …
active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro‐molar …
Development and future prospects of selective organometallic compounds as anticancer drug candidates exhibiting novel modes of action
S Parveen, F Arjmand, S Tabassum - European Journal of Medicinal …, 2019 - Elsevier
Organometallic complexes have widely been used for the treatment of various diseases viz.,
malaria, arthritis, syphilis, pernicious anemia, tuberculosis and particular in cancers. Recent …
malaria, arthritis, syphilis, pernicious anemia, tuberculosis and particular in cancers. Recent …
Mechanistic insights into a novel chromone-appended Cu (II) anticancer drug entity: in vitro binding profile with DNA/RNA substrates and cytotoxic activity against …
I Yousuf, F Arjmand, S Tabassum, L Toupet… - Dalton …, 2015 - pubs.rsc.org
A new chromone-appended Cu (II) drug entity (1) was designed and synthesized as a
potential anticancer chemotherapeutic agent. The structural elucidation was carried out …
potential anticancer chemotherapeutic agent. The structural elucidation was carried out …
H2 and carbon-heteroatom bond activation mediated by polarized heterobimetallic complexes
RM Charles III, TP Brewster - Coordination chemistry reviews, 2021 - Elsevier
The field of heterobimetallic chemistry has rapidly expanded over the last decade. In
addition to their interesting structural features, heterobimetallic structures have been found …
addition to their interesting structural features, heterobimetallic structures have been found …
Nuclear blebbing of biologically active organoselenium compound towards human cervical cancer cell (HeLa): In vitro DNA/HSA binding, cleavage and cell imaging …
New pharmacophore organoselenium compound (1) was designed, synthesized and
characterized by various spectroscopic methods (IR, ESI–MS, 1 H, 13 C and 77 Se NMR) …
characterized by various spectroscopic methods (IR, ESI–MS, 1 H, 13 C and 77 Se NMR) …
Comparative study of the antiproliferative activity of heterometallic carbene gold (I)–platinum (II) and gold (I)–palladium (II) complexes in cancer cell lines
MC Dietl, M Maag, S Ber, F Rominger, M Rudolph… - Chemical …, 2024 - pubs.rsc.org
The stepwise, one-pot synthesis of heterobimetallic carbene gold (I) platinum (II) complexes
from readily available starting materials is presented. The protecting group free methodology …
from readily available starting materials is presented. The protecting group free methodology …
Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands
SJ Allison, M Sadiq, E Baronou, PA Cooper, C Dunnill… - Cancer letters, 2017 - Elsevier
Organometallic complexes offer the prospect of targeting multiple pathways that are
important in cancer biology. Here, the preclinical activity and mechanism (s) of action of a …
important in cancer biology. Here, the preclinical activity and mechanism (s) of action of a …
Design, synthesis and characterisation of new chimeric ruthenium (II)–gold (I) complexes as improved cytotoxic agents
Two heterobimetallic complexes, ie [RuCl2 (p-cymene)(μ-dppm) AuC](1) and [RuCl2 (p-
cymene)(μ-dppm) Au (S-thiazoline)](3), based on known cytotoxic [Ru (p-cymene) Cl2 …
cymene)(μ-dppm) Au (S-thiazoline)](3), based on known cytotoxic [Ru (p-cymene) Cl2 …
Multi-target metal-based anticancer agents
There has been a growing interest in the rational design of multi-targeted drugs with the aim
of enhancing overall efficacy and/or improving safety. The development of multi-targeted …
of enhancing overall efficacy and/or improving safety. The development of multi-targeted …