Inactivation of the CDKN2A Tumor-Suppressor Gene by Deletion or Methylation Is Common at Diagnosis in Follicular Lymphoma and Associated with Poor Clinical …

A Alhejaily, AG Day, HE Feilotter, T Baetz… - Clinical Cancer …, 2014 - AACR
Purpose: Follicular lymphoma, the most common indolent lymphoma, is clinically
heterogeneous. CDKN2A encodes the tumor suppressors p16INK4a and p14ARF and …

Abundant expression of interleukin-21 receptor in follicular lymphoma cells is associated with more aggressive disease

B Wood, S Sikdar, SJ Choi, S Virk, A Alhejaily… - Leukemia & …, 2013 - Taylor & Francis
Abstract Recombinant interleukin-21 (IL-21) has potential utility in cancer therapy.
Stimulation with IL-21 can induce apoptosis in follicular lymphoma (FL) cells, and existing …

Quantitative analysis of CDKN2A methylation, mRNA, and p16INK4a protein expression in children and adolescents with Burkitt lymphoma: Biological and clinical …

MCS Robaina, RS Faccion, VO Arruda… - Leukemia Research, 2015 - Elsevier
CDKN2A is a tumor suppressor gene critical in the cell cycle regulation. Little is known
regarding the role of CDKN2A methylation in the pathogenesis of Burkitt lymphoma (BL) …

p63 and p53 expression in extranodal NK/T cell lymphoma, nasal type

Z Ye, Q Cao, G Niu, Y Liang, Y Liu, L Jiang… - Journal of clinical …, 2013 - jcp.bmj.com
Objectives To investigate the pathological and clinical meaning of p63 in extranodal nasal
type NK/T cell lymphoma (NKTCL). Methods We detected p63 and p53 expression using …

Abundant expression of BMI1 in follicular lymphoma is associated with reduced overall survival

N AlJohani, SJ Choi, AG Day, A Alhejaily… - Leukemia & …, 2018 - Taylor & Francis
Although generally indolent, follicular lymphoma (FL) sometimes pursues a more aggressive
course leading to early death. B-cell-specific Mo-MLV insertion site-1 (BMI1) is a member of …

Tumor suppressors in follicular lymphoma

C Graham, DP LeBrun - Leukemia & Lymphoma, 2015 - Taylor & Francis
Follicular lymphoma (FL) is the most common indolent lymphoma. The vast majority of cases
are associated with the chromosome translocation t (14; 18), a somatic rearrangement that …

Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with …

L Chen, K Tyryshkin, A Moore, DW Scott… - Leukemia & …, 2020 - Taylor & Francis
Up-regulation of BCL2 in cases of diffuse large B-cell lymphoma (DLBCL) can confer
treatment resistance. Quantitative immunofluorescence (QIF) histology allows objective …

[PDF][PDF] INSIGHT INTO THE PATHOGENESIS OF FOLLICULAR LYMPHOMA

A Alhejaily - srfederation.org
Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL). FL is
clinically designated as an indolent with a long median survival of 8-10 years. However, the …

[图书][B] Defining clinically relevant subgroups of follicular lymphoma cases according to the functional status of the CDKN2A gene

AG Alhejaily - 2013 - search.proquest.com
Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL). FL is
clinically designated as an indolent disease with a long median survival of 8-10 years …

[PDF][PDF] Chapter Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is …

L Pascal, C Anne - 2011 - library.oapen.org
In eukaryotic cells, DNA replication and mitosis are the two processes allowing cell division
and generation of two identical daughter cells without loss or alterations of genetic …