Mechanisms of clathrin-mediated endocytosis

M Kaksonen, A Roux - Nature reviews Molecular cell biology, 2018 - nature.com
Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

Energy costs of salt tolerance in crop plants

R Munns, DA Day, W Fricke, M Watt, B Arsova… - New …, 2020 - Wiley Online Library
Agriculture is expanding into regions that are affected by salinity. This review considers the
energetic costs of salinity tolerance in crop plants and provides a framework for a …

In situ architecture of the ER–mitochondria encounter structure

MR Wozny, A Di Luca, DR Morado, A Picco, R Khaddaj… - Nature, 2023 - nature.com
The endoplasmic reticulum and mitochondria are main hubs of eukaryotic membrane
biogenesis that rely on lipid exchange via membrane contact sites,–, but the underpinning …

Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

LB Case, X Zhang, JA Ditlev, MK Rosen - Science, 2019 - science.org
Biomolecular condensates concentrate macromolecules into foci without a surrounding
membrane. Many condensates appear to form through multivalent interactions that drive …

Design of biologically active binary protein 2D materials

AJ Ben-Sasson, JL Watson, W Sheffler, MC Johnson… - Nature, 2021 - nature.com
Ordered two-dimensional arrays such as S-layers, and designed analogues,–have intrigued
bioengineers,, but with the exception of a single lattice formed with flexible linkers, they are …

Molecular mechanisms of endomembrane trafficking in plants

F Aniento, V Sánchez de Medina Hernández… - The Plant …, 2022 - academic.oup.com
Endomembrane trafficking is essential for all eukaryotic cells. The best-characterized
membrane trafficking organelles include the endoplasmic reticulum (ER), Golgi apparatus …

Condensation of Ede1 promotes the initiation of endocytosis

M Kozak, M Kaksonen - Elife, 2022 - elifesciences.org
Clathrin-mediated endocytosis is initiated by a network of weakly interacting proteins
through a poorly understood mechanism. Ede1, the yeast homolog of mammalian Eps15, is …

WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues

F Gaertner, P Reis-Rodrigues, I De Vries, M Hons… - Developmental cell, 2022 - cell.com
When crawling through the body, leukocytes often traverse tissues that are densely packed
with extracellular matrix and other cells, and this raises the question: How do leukocytes …

Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis

M Akamatsu, R Vasan, D Serwas, MA Ferrin… - Elife, 2020 - elifesciences.org
Force generation by actin assembly shapes cellular membranes. An experimentally
constrained multiscale model shows that a minimal branched actin network is sufficient to …

Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells

KA Sochacki, AM Dickey, MP Strub, JW Taraska - Nature cell biology, 2017 - nature.com
Dozens of proteins capture, polymerize and reshape the clathrin lattice during clathrin-
mediated endocytosis (CME). How or if this ensemble of proteins is organized in relation to …