Adaptation is an essential feature of auditory neurons, which reduces their responses to
unchanging and recurring sounds and allows their response properties to be matched to the …

Stimulus-specific adaptation (SSA) is the reduction in responses to frequent stimuli
(standards) that does not generalize to rare stimuli (deviants). We investigated the …

Most animals display robust parental behaviors that support the survival and well-being of
their offspring. The manifestation of parental behaviors is accompanied by physiological and …

Even a transient period of hearing loss during the developmental critical period can induce
long-lasting deficits in temporal and spectral perception. These perceptual deficits correlate …

The accumulation of α-synuclein induces neuronal loss in midbrain nuclei and leads to the
disruption of motor circuits, while the pathology of α-synuclein in cortical regions remains …

SYNGAP1 haploinsufficiency-related intellectual disability (SYNGAP1-ID) is characterized
by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory …

Background Hearing impairment is a risk factor for schizophrenia. Patients with 22q11. 2
deletion syndrome have a 25% to 30% risk of schizophrenia, and up to 60% also have …

Roughly 20% of the neurons in the mouse cortex are inhibitory interneurons (INs). Of these,
the three major subtypes are parvalbumin (PV), somatostatin (SST), and vasoactive …

Background The 22q11. 2 chromosomal microdeletion is one of the strongest known genetic
risk factors for schizophrenia;~ 30% of carriers develop schizophrenia in adulthood. Up to …

Abstract The 22q11. 2 deletion is a risk factor for multiple psychiatric disorders including
schizophrenia and also increases vulnerability to middle-ear problems that can cause …