Biomimetic affinity chromatography with short peptide ligands, as a promising bioseparation
technique, has great potential to protein separation and purification, which is based on …

The interest in therapeutic monoclonal antibodies (mAbs) has significantly grown in the
pharmaceutical industry, exceeding 100 FDA mAbs approved. Although the upstream …

Following the consolidation of therapeutic proteins in the fight against cancer, autoimmune,
and neurodegenerative diseases, recent advancements in biochemistry and biotechnology …

From the initial steps of early drug discovery, the traditional techniques, like docking, QSAR,
or molecular dynamics, have been used for decades identifying targets, ranking molecule …

Peptide ligands are widely used in protein purification by affinity chromatography. Here, we
applied a fully automated two-stage library screening method that avoids false positive …

Bevacizumab is a vascular endothelial growth factor (VEGF)-directed monoclonal antibody
(mAb) used for the treatment of several human cancers. Given that bevacizumab is …

Nowadays, treatment with specific antivenins is considered the only cure for snakebites
accidents. However, access to antivenom obstructs the successful implementation of the …

Peptide KVPLITVSKAK was selected to design a synthetic ligand for affinity chromatography
purification of recombinant human follicle stimulating hormone (rhFSH), based on the …

From the initial steps of early drug discovery, the traditional techniques, like docking, QSAR,
or molecular dynamics, have been used for decades identifying targets, ranking molecule …

The interest in therapeutic monoclonal antibodies (mAbs) has significantly grown in the
pharmaceutical industry, exceeding 100 FDA mAbs approved. Although the upstream …