OBJECTIVE: Tumor necrosis factor (TNF) antagonists fall into 2 classes: etanercept (ETA) is
a soluble TNF receptor, while infliximab (INF) and adalimumab (ADA) are monoclonal …

γδ T cells are a functionally heterogeneous population and contribute to many early immune
responses. The majority of their activity is described in humans and mice, but the immune …

Reactivation of cytomegalovirus (CMV) remains a serious complication after allogeneic stem
cell transplantation, but the role of γδ T cells is undefined. We have studied the immune …

Malignant ascites caused by peritoneal dissemination of gastric cancer is chemotherapy‐
resistant and associated with poor prognosis. We conducted a pilot study to evaluate the …

The earliest defense against microbial infection is represented by the responses of the
innate (or natural) immune system, that also profoundly regulates the adaptive (or acquired) …

The complex antiviral immune mechanisms involve both adaptive and innate reactions
mediated by γδ T lymphocytes, whose unique immunosurveillance contributions are …

Brucellosis is a worldwide human zoonosis caused by intracellular bacteria of the genus
Brucella. Virulence factors play an important role in allowing Brucella infection and …

The detailed characterization of human γδ T lymphocyte differentiation at the single-cell
transcriptomic (scRNAseq) level in tumors and patients with coronavirus disease 2019 …

Human Vγ9Vδ2 T cells recognize nonpeptidic Ags generated by the 1-deoxy-d-xylulose 5-
phosphate (many eubacteria, algae, plants, and Apicomplexa) and mevalonate (eukaryotes …

Objective: γδ T cells bearing the Vγ9Vδ2 T-cell receptor exert many antiviral effector
functions in humans, including release of anti-HIV factors and direct cytotoxicity against virus …