Therapeutic drug monitoring (TDM) opens the door to personalized medicine, yet it is
infrequently applied to β‐lactam antibiotics, one of the most commonly prescribed drug …

Intravenous β‐lactam antibiotics remain a cornerstone in the management of bacterial
infections due to their broad spectrum of activity and excellent tolerability. β‐lactams are well …

Beta-lactams remain a critical member of our antibiotic armamentarium and are among the
most commonly prescribed antibiotic classes in the inpatient setting. For these agents, the …

Cystic fibrosis affects several organs, predisposing patients to severe bacterial respiratory
infections, including those caused by methicillin-resistant Staphylococcus aureus. Cystic …

SUMMARY The World Health Organisation's 2022 AWaRe Book provides guidance for the
use of 39 antibiotics to treat 35 infections in primary healthcare and hospital facilities. We …

Intravenous beta-lactam antibiotics are the most prescribed antibiotic class in US
hospitalized patients of all ages; therefore, optimizing their dosing is crucial. Bactericidal …

Background There is no consensus about which outcomes should be evaluated in studies of
pulmonary exacerbations in people with cystic fibrosis (CF). Outcomes used for evaluation …

Introduction Medicine use in children with cystic fibrosis (CF) is complicated by inconsistent
pharmacokinetics at variance with the general population, a lack of research into this and its …

Antibiotic therapy is one of the main treatments for cystic fibrosis (CF). It aims to eradicate
bacteria during early infection, calms down the inflammatory process, and leads to symptom …

Objectives Cystic fibrosis (CF) acute pulmonary exacerbations are often caused by
Pseudomonas aeruginosa, including multi-drug resistant strains. Optimal antibiotic therapy …