Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in
recent decades, causing large-scale epidemics in many parts of the world. CHIKV infection …

Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing
machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3 …

Alphaviruses are positive-strand RNA viruses, typically transmitted by mosquitoes between
vertebrate hosts. They encode four essential replication proteins, the non-structural proteins …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic that
originated in Wuhan, China, in December 2019 has impacted public health, society, the …

RNA methyltransferases (MTases) are ubiquitous enzymes whose hitherto low profile in
medicinal chemistry, contrasts with the surging interest in RNA methylation, the arguably …

Chikungunya fever (CHIKF) is an arbovirus disease caused by chikungunya virus (CHIKV),
an alphavirus of Togaviridae family. Transmission follows a human-mosquito-human cycle …

Many viruses encode RNA-modifying enzymes to edit the 5′ end of viral RNA to mimic the
cellular mRNA for effective protein translation, genome replication, and evasion of the host …

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has spread to more
than 60 countries worldwide. CHIKV infection leads to a febrile illness known as …

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that can cause a
debilitating disease that is primarily characterized by persistent joint pain. CHIKV has been …

The consequences of infection with severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) can range from asymptomatic to fatal disease. Variations in epithelial susceptibility to …