Clavulanic acid (CA) is an irreversible β-lactamase enzyme inhibitor with a weak
antibacterial activity produced by Streptomyces clavuligerus (S. clavuligerus). CA is typically …

Microorganisms have provided a rich source of therapeutically valuable natural products.
Recent advances in whole genome sequencing and bioinformatics have revealed immense …

Clavulanic acid (CA) is a clinically important secondary metabolite used to treat infectious
diseases. We aimed to decipher complex regulatory mechanisms acting in CA biosynthesis …

Since a transcriptional regulator has yet to be identified within the tunicamycin biosynthetic
gene cluster in Streptomyces clavuligerus, we conducted a comprehensive investigation by …

Abstract lysA gene encoding meso-diaminopimelic acid (DAP) decarboxylase enzyme that
catalyzes l-lysine biosynthesis in the aspartate pathway in Streptomyces clavuligerus was …