Environmental exposures associated with elevated risk for autism spectrum disorder may augment the burden of deleterious de novo mutations among probands

K Pugsley, SW Scherer, MA Bellgrove, Z Hawi - Molecular psychiatry, 2022 - nature.com
Although the full aetiology of autism spectrum disorder (ASD) is unknown, familial and twin
studies demonstrate high heritability of 60–90%, indicating a predominant role of genetics in …

Role of autophagy in cadmium‐induced hepatotoxicity and liver diseases

S Niture, M Lin, Q Qi, JT Moore, KE Levine… - Journal of …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic pollutant that is associated with several severe human diseases. Cd
can be easily absorbed in significant quantities from air contamination/industrial pollution …

A review on nanotoxicity and nanogenotoxicity of different shapes of nanomaterials

E Demir - Journal of Applied Toxicology, 2021 - Wiley Online Library
Nanomaterials (NMs) generally display fascinating physical and chemical properties that are
not always present in bulk materials; therefore, any modification to their size, shape, or …

Silicon alleviates cadmium stress in basil (Ocimum basilicum L.) through alteration of phytochemical and physiological characteristics

J Gheshlaghpour, B Asghari, R Khademian… - Industrial Crops and …, 2021 - Elsevier
Cadmium (Cd) toxicity can disorder normal plant growth and development causing
catastrophic crop failures and food insecurity. Silicon (Si) plays a pivotal role in mitigation of …

Physicochemical properties, pharmacokinetics, toxicology and application of nanocarriers

X Cai, M Jin, L Yao, B He, S Ahmed, W Safdar… - Journal of Materials …, 2023 - pubs.rsc.org
As a promising delivery nanosystem for drug controlled-release, nanocarriers (NCs) have
been investigated widely. Although various studies have concentrated on the preparation …

Cadmium modulates steatosis, fibrosis, and oncogenic signaling in liver cancer cells by activating notch and AKT/mTOR pathways

S Niture, S Gadi, M Lin, Q Qi, SS Niture… - Environmental …, 2023 - Wiley Online Library
Cadmium (Cd) is an environmental pollutant that increases hepatotoxicity and the risk of
liver diseases. In the current study, we investigated the effect of a physiologically relevant …

An in vivo study of nanorod, nanosphere, and nanowire forms of titanium dioxide using Drosophila melanogaster: toxicity, cellular uptake, oxidative stress, and DNA …

E Demir - Journal of Toxicology and Environmental Health, Part A, 2020 - Taylor & Francis
The biological impact of nanomaterials (NMs) is determined by several factors such as size
and shape, which need to be taken into consideration in any type of analysis. While …

Mechanism of cadmium-induced nephrotoxicity

CJ Bautista, N Arango, P Consuelo, IB Mitre-Aguilar… - Toxicology, 2024 - Elsevier
Heavy metals are found naturally in our environment and have many uses and applications
in daily life. However, high concentrations of metals may be a result of pollution due to …

Mechanisms and biological impacts of graphene and multi‐walled carbon nanotubes on Drosophila melanogaster: Oxidative stress, genotoxic damage, phenotypic …

E Demir - Journal of Applied Toxicology, 2022 - Wiley Online Library
The use of graphene and multi‐walled carbon nanotubes (MWCNTs) has now become
rather common in medical applications as well as several other areas thanks to their useful …

Consequences of a short-term exposure to a sub lethal concentration of CdO nanoparticles on key life history traits in the fruit fly (Drosophila melanogaster)

S El Kholy, JP Giesy, Y Al Naggar - Journal of hazardous materials, 2021 - Elsevier
Nanoparticles of cadmium oxide (CdO NPs) are among the most common industrial metal
oxide nanoparticles. Early adulthood (P1) fruit flies (D. melanogaster) were exposed for 7 …