Brains contain networks of interconnected neurons and so knowing the network architecture is essential for understanding brain function. We therefore mapped the synaptic-resolution …
In the last decade, researchers using Drosophila melanogaster have made extraordinary progress in uncovering the mysteries underlying learning and memory. This progress has …
Making inferences about the computations performed by neuronal circuits from synapse- level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
J Lu, AH Behbahani, L Hamburg, EA Westeinde… - Nature, 2022 - nature.com
When an animal moves through the world, its brain receives a stream of information about the body's translational velocity from motor commands and sensory feedback signals. These …
I Titos, A Juginović, A Vaccaro, K Nambara, P Gorelik… - Cell, 2023 - cell.com
Suppressing sensory arousal is critical for sleep, with deeper sleep requiring stronger sensory suppression. The mechanisms that enable sleeping animals to largely ignore their …
As connectomics advances, it will become commonplace to know far more about the structure of a nervous system than about its function. The starting point for many …
M Corrales, BT Cocanougher, AB Kohn… - Neural …, 2022 - Springer
Molecular profiles of neurons influence neural development and function but bridging the gap between genes, circuits, and behavior has been very difficult. Here we used single cell …
In dynamic environments, animals make behavioural decisions on the basis of the innate valences of sensory cues and information learnt about these cues across multiple …
Y Shuai, M Sammons, G Sterne, K Hibbard, H Yang… - eLife, 2024 - elifesciences.org
The mushroom body (MB) is the center for associative learning in insects. In Drosophila, intersectional split-GAL4 drivers and electron microscopy (EM) connectomes have laid the …