Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

KG Fosnacht, MD Pluth - Chemical Reviews, 2024 - ACS Publications
Hydrogen sulfide (H2S) is not only a well-established toxic gas but also an important small
molecule bioregulator in all kingdoms of life. In contemporary biology, H2S is often classified …

Label-free bioassay with graphene oxide-based fluorescent aptasensors: A review

K Ma, X Li, B Xu, W Tian - Analytica Chimica Acta, 2021 - Elsevier
Bioassays using a fluorophore and DNA aptamer have been extensively developed due to
the ultrasensitivity of fluorophores and recognition ability of DNA aptamers. Conventional …

Hydrolysis-resistant ester-based linkers for development of activity-based NIR bioluminescence probes

AK Yadav, Z Zhao, Y Weng, SH Gardner… - Journal of the …, 2023 - ACS Publications
Activity-based sensing (ABS) probes equipped with a NIR bioluminescence readout are
promising chemical tools to study cancer biomarkers owing to their high sensitivity and deep …

Recent process in organic small molecular fluorescent probes for tracking markers of tumor redox balance

Z Wu, Y Guo, W Jiang, Y Yang, P Wei, T Yi - TrAC Trends in Analytical …, 2024 - Elsevier
Exploring the redox balance in tumor region is of great significance for clarifying the
pathogenesis of tumors and finding methods for the treatment of tumors. Tumors can …

A review of chemical tools for studying small molecule persulfides: detection and delivery

KM Dillon, JB Matson - ACS chemical biology, 2021 - ACS Publications
Hydrogen sulfide (H2S) has gained significant attention as a potent bioregulator in the redox
metabolome, but it is just one of many reactive sulfur species (RSS). Recently, small …

H2S2-triggered off-on fluorescent indicator with endoplasmic reticulum targeting for imaging in cells and zebrafishes

H Zhou, J Tang, L Sun, J Zhang, B Chen, J Kan… - Sensors and Actuators B …, 2019 - Elsevier
Reactive sulfur species (RSS) play important physiological and pathological roles in
biological redox homeostasis, cell signaling and the regulation of metabolism. Recent …

Engineering a highly selective probe for ratiometric imaging of H 2 S n and revealing its signaling pathway in fatty liver disease

W Li, L Wang, S Yin, H Lai, L Yuan, X Zhang - Chemical Science, 2020 - pubs.rsc.org
Hydrogen polysulfides (H2Sn, n> 1) have continuously been proved to act as important
signal mediators in many physiological processes. However, the physiological role of H2Sn …

Development of a Bioorthogonal Click-to-Release Reaction for Hydrogen Polysulfide (H2Sn) Detection

X Tong, J Chen, M Wang, J Liu, J Li, X Wang… - Analytical …, 2024 - ACS Publications
In this study, we present an innovative “click-to-release” strategy for the design of highly
specific H2S n bioorthogonal probes that undergo a specific click reaction with H2S n and …

A novel flavone-based ESIPT ratiometric fluorescent probe for selective sensing and imaging of hydrogen polysulfides

L Yang, N Yang, P Gu, C Wang, B Li, Y Zhang… - … Acta Part A: Molecular …, 2022 - Elsevier
Hydrogen polysulfides (H 2 S n) as an important member of reactive sulfur species is closely
relevant to many physiological functions in redox homeostasis and metabolism. Dual …

Fluorescent probes and selective inhibitors for biological studies of hydrogen sulfide-and polysulfide-mediated signaling

Y Takano, H Echizen, K Hanaoka - Antioxidants & redox signaling, 2017 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) plays roles in many physiological processes,
including relaxation of vascular smooth muscles, mediation of neurotransmission, inhibition …