The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Abstract Purpose of Review The rapid spread of virus, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has turned out to be a global emergency. Symptoms of this …

Background Chronic alcohol exposure (CAE) during late adolescence increases the risk of
anxiety development. Alcohol-induced prefrontal cortex (PFC) microglial activation …

The world is fuming at SARS-CoV-2 for being the culprit for causing the devastating COVID-
19, claiming millions of lives across the globe in the form of respiratory disorders. But lesser …

Despite low levels of cannabinoid receptor type 2 (CB2R) expression in the central nervous
system in human and rodents, a growing body of evidence shows CB2R involvement in …

Endocannabinoids (eCBs) are lipid-based retrograde messengers with a relatively short half-
life that are produced endogenously and, upon binding to the primary cannabinoid receptors …

The inflammation process represents of a dynamic series of phenomena that manifest
themselves with an intense vascular reaction. Neuroinflammation is a reply from the central …

Objective Chaihu Shugan San (CSS) is a common antidepressant prescription in traditional
Chinese medicines. However, its active ingredients and mechanisms are unknown. The aim …

Spermidine is a naturally occurring endogenous polyamine synthesized from diamine
putrescine. It is a well-known autophagy inducer that maintains cellular and neuronal …

Cannabis sativa L. is increasingly emerging for its protective role in modulating
neuroinflammation, a complex process orchestrated among others by microglia, the resident …