Beneficial outcomes of omega-6 and omega-3 polyunsaturated fatty acids on human health: An update for 2021

I Djuricic, PC Calder - Nutrients, 2021 - mdpi.com
Oxidative stress and inflammation have been recognized as important contributors to the risk
of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate …

Metabolic orchestration of the wound healing response

SA Eming, PJ Murray, EJ Pearce - Cell metabolism, 2021 - cell.com
Wound healing requires cooperation between different cell types, among which
macrophages play a central role. In particular, inflammatory macrophages are engaged in …

NSAIDs and cancer resolution: new paradigms beyond cyclooxygenase

OR Kolawole, K Kashfi - International journal of molecular sciences, 2022 - mdpi.com
Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

Modulation of redox-sensitive transcription factors with polyphenols as pathogenetically grounded approach in therapy of systemic inflammatory response

V Kostenko, O Akimov, O Gutnik, H Kostenko… - Heliyon, 2023 - cell.com
One of the adverse outcomes of acute inflammatory response is progressing to the chronic
stage or transforming into an aggressive process, which can develop rapidly and result in …

Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases

Z Chen, W Ding, X Yang, T Lu, Y Liu - Journal of ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Licorice is a medicinal herb with a 2000-year history of
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …

SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor

MW Alnouri, KA Roquid, R Bonnavion, H Cho… - Proceedings of the …, 2024 - pnas.org
Inflammation is a protective response to pathogens and injury. To be effective it needs to be
resolved by endogenous mechanisms in order to avoid prolonged and excessive …

Anti-inflammatory and anticancer effects of microalgal carotenoids

J Ávila-Román, S García-Gil, A Rodríguez-Luna… - Marine Drugs, 2021 - mdpi.com
Acute inflammation is a key component of the immune system's response to pathogens, toxic
agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing …

Inflammation and resolution in obesity

M Soták, M Clark, BE Suur, E Börgeson - Nature Reviews …, 2024 - nature.com
Inflammation is an essential physiological defence mechanism, but prolonged or excessive
inflammation can cause disease. Indeed, unresolved systemic and adipose tissue …

Resolvin T-series reduce neutrophil extracellular traps

N Chiang, M Sakuma, AR Rodriguez… - Blood, The Journal …, 2022 - ashpublications.org
The newly identified 13-series (T-series) resolvins (RvTs) regulate phagocyte functions and
accelerate resolution of infectious inflammation. Because severe acute respiratory syndrome …

A cross-talk between sestrins, chronic inflammation and cellular senescence governs the development of age-associated sarcopenia and obesity

G Livshits, A Kalinkovich - Ageing Research Reviews, 2023 - Elsevier
The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …